Evidence map›Paper›PMID 32351389›Full record

ArticleFrontiers in pharmacology2020

Impact of a Multifaceted Pharmacist-Led Intervention on Antimicrobial Stewardship in a Gastroenterology Ward: A Segmented Regression Analysis.

Yaling Du, Jing Li, Xinchun Wang, Xi Peng, Xiaoyi Wang, Wenying He, Yan Li, Xuemei Wang, Qiuxia Yang, Xinping Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  4. Observational
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  15. The role of the clinical pharmacist in antimicrobial stewardship in Asia: A review.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2022
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yaling DuSchool of Medicine and Health Management, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jing LiFirst Affiliated Hospital, School of Medicine, Shihezi University, Shihezi, China.
Xinchun WangFirst Affiliated Hospital, School of Medicine, Shihezi University, Shihezi, China.
Xi PengFirst Affiliated Hospital, School of Medicine, Shihezi University, Shihezi, China.
Xiaoyi WangFirst Affiliated Hospital, School of Medicine, Shihezi University, Shihezi, China.
Wenying HeFirst Affiliated Hospital, School of Medicine, Shihezi University, Shihezi, China.
Yan LiFirst Affiliated Hospital, School of Medicine, Shihezi University, Shihezi, China.
Xuemei WangSchool of Medicine and Health Management, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Qiuxia YangSchool of Medicine and Health Management, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xinping ZhangSchool of Medicine and Health Management, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
First Affiliated Hospital of Shihezi University Medical College · CNHuazhong University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIrrational use of antimicrobial agents for gastrointestinal diseases deserves attention, but corresponding antimicrobial stewardship programs (ASPs) are generally not a priority for managers. We conducted this study to evaluate the effectiveness of multifaceted pharmacist-led (MPL) interventions in the gastroenterology ward (GW) to provide evidence for the efficacy of ASPs in a non-priority department.

methodsThis was an interventional, retrospective study implemented in China. The MPL intervention lasting 1.5 years involved daily ward rounds with physicians, regular review of medical orders, monthly indicator feedback, frequent physician training, and necessary patient education. Data on all hospitalized adults receiving antibiotics was extracted from the hospital information system over a 36-month period from January 2016 to December 2018. Segmented regression analysis of interrupted time series was performed to evaluate the effect of the MPL interventions (started in July 2017) on antibiotic use and length of hospital stay, which was calculated monthly as analytical units.

resultsA total of 1763 patients receiving antibiotics were enrolled. Segmented regression models showed descending trends from the baseline in the intensity of antibiotic consumption (coefficient = -0.88,

conclusionThe MPL interventions led a statistically significant decline in the number of patients receiving antibiotics, the antibiotic consumption, and the average hospital stay post-intervention compared to the pre-intervention phase of the study. Health policymakers should actively practice MPL interventions by clinical pharmacists in ASPs in those departments that are not included in priority management.

Indexed as

antimicrobial stewardshipgastroenterologyimpact assessmentmultifaceted interventionpharmacist rolesegmented regression

Identifiers

PMID32351389
PMCPMC7174747
OpenAlexW3016609365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.