Evidence map›Paper›PMID 32351367›Full record

ArticleFrontiers in neuroanatomy2020

How Human Is Human Connectional Neuroanatomy?

R Jarrett Rushmore, Sylvain Bouix, Marek Kubicki, Yogesh Rathi, Edward H Yeterian, Nikos Makris

Abstract read
In one paragraph

Article in Frontiers in neuroanatomy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

R Jarrett RushmoreDepartment of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, United States.
Sylvain BouixPsychiatric Neuroimaging Laboratory, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, United States.
Marek KubickiPsychiatric Neuroimaging Laboratory, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, United States.
Yogesh RathiPsychiatric Neuroimaging Laboratory, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, United States.
Edward H YeterianPsychiatric Neuroimaging Laboratory, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, United States.
Nikos MakrisDepartment of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, United States.

Funding

High Resolution, Comprehensive Atlases of the Human Brain MorphologyR01MH112748 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI BOUIX, SYLVAIN, KUBICKI, MAREK · 2018 to 2022
$4.1M
Mentoring and neuroimaging research on new targets for DBS in OCDK24MH116366 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI MAKRIS, NIKOLAOS · 2018 to 2022
$817k
NIMH NIH HHS K24 MH116366NIMH NIH HHS R01 MH112748
6 · The paper itself

Abstract

The structure of the human brain has been studied extensively. Despite all the knowledge accrued, direct information about connections, from origin to termination, in the human brain is extremely limited. Yet there is a widespread misperception that human connectional neuroanatomy is well-established and validated. In this article, we consider what is known directly about human structural and connectional neuroanatomy. Information on neuroanatomical connections in the human brain is derived largely from studies in non-human experimental models in which the entire connectional pathway, including origins, course, and terminations, is directly visualized. Techniques to examine structural connectivity in the human brain are progressing rapidly; nevertheless, our present understanding of such connectivity is limited largely to data derived from homological comparisons, particularly with non-human primates. We take the position that an in-depth and more precise understanding of human connectional neuroanatomy will be obtained by a systematic application of this homological approach.

Indexed as

axonscatDTIhomologyhumanmonkeyneuroanatomyrat

Identifiers

PMID32351367
PMCPMC7176274

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.