Evidence map›Paper›PMID 32351353›Full record

ReviewFrontiers in neuroscience2020

Rhodopsin: A Potential Biomarker for Neurodegenerative Diseases.

Cameron Lenahan, Rajvee Sanghavi, Lei Huang, John H Zhang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Novel Biologically ActiveMolecules (Basel, Switzerland) · 2023
    Article
  12. Review
  13. Review
  14. Article
  15. Evolution of the Automatic Rhodopsin Modeling (ARM) Protocol.Topics in current chemistry (Cham) · 2022
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cameron LenahanBurrell College of Osteopathic Medicine, Las Cruces, NM, United States.
Rajvee SanghaviBurrell College of Osteopathic Medicine, Las Cruces, NM, United States.
Lei HuangCenter for Neuroscience Research, Loma Linda University School of Medicine, Loma Linda, CA, United States.
John H ZhangCenter for Neuroscience Research, Loma Linda University School of Medicine, Loma Linda, CA, United States.
Loma Linda University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinal alterations have recently been associated with numerous neurodegenerative diseases. Rhodopsin is a G-protein coupled receptor found in the rod cells of the retina. As a biomarker associated with retinal thinning and degeneration, it bears potential in the early detection and monitoring of several neurodegenerative diseases. In this review article, we summarize the findings of correlations between rhodopsin and several neurodegenerative disorders as well as the potential of a novel technique, cSLO, in the quantification of rhodopsin.

Indexed as

Alzheimer’s diseaseamyotrophic lateral sclerosisconfocal scanning laser ophthalmoscopyHuntington’s diseaseParkinson’s diseaserhodopsin

Identifiers

PMID32351353
PMCPMC7175229
OpenAlexW3017103365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.