Evidence map›Paper›PMID 32351290›Full record

ReviewWorld journal of gastroenterology2020

Update on quinolone-containing rescue therapies for

Hideki Mori, Hidekazu Suzuki

Registry-linked trialAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05863858 (High Eradication Rate of Helicobacter Pylori Infection With Moxifloxacin-Based Triple Therapy in Comparison With Levofloxacin-Based Sequential Therapy), which is not on this map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05863858 phase3completednot on this map

High Eradication Rate of Helicobacter Pylori Infection With Moxifloxacin-Based Triple Therapy in Comparison With Levofloxacin-Based Sequential Therapy: Randomized Controlled Trials

TypeinterventionalSponsorIyad Naeem Muhammad, PhDRan2020 to 2022Enrolled162ConditionsHelicobacter Pylori Infection, Helicobacter Pylori Infection, Susceptibility toArmsSequential Regimen: Levofloxacin 500 mg BID, Amoxicillin 1 gm BID, omeprazole 20 mg BID for first five days followed by Levofloxacin 500 mgBID, Tinidazole 500 mg BID, Omeprazole 20 mg BID, Triple Regimen: Moxifloxacin 400mg OD, Amoxicillin 1 gm BID, Omeprazole 20mgBID
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. First regional consensus on the management ofWorld journal of gastroenterology · 2025
    Guideline
  2. Third-line and rescue therapy for refractoryWorld journal of gastroenterology · 2023
    Pooled it
  3. Pooled it
  4. Review
  5. Helicobacter pylori Management in Older Adults: Current Perspectives From Japan.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Review
  6. TargetingJournal of clinical biochemistry and nutrition · 2025
    Article
  7. Article
  8. Article
  9. Overcoming antibiotic-resistantWorld journal of gastroenterology · 2025
    Review
  10. Article
  11. Tailored Therapy Using Bismuth Add-on Standard Triple Therapy vs. Concomitant Therapy: A First-line Regimen forThe Korean journal of helicobacter and upper gastrointestinal research · 2023
    Article
  12. Primary Antibiotic Resistance ofPathogens (Basel, Switzerland) · 2022
    Review
  13. Article
  14. Sitafloxacin for Third-LineJournal of clinical medicine · 2021
    Review
  15. Article
  16. Article
  17. BestAntibiotics (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hideki MoriDepartment of Clinical and Experimental Medicine, Translational Research Center for Gastrointestinal Disorders, University of Leuven, Leuven 3000, Belgium. hideki.mori@kuleuven.be.
Hidekazu SuzukiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara 259-1193, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Third generation of quinolones, such as levofloxacin and moxifloxacin, -containing regimens are often used in second-line or rescue treatment of

Indexed as

Anti-Bacterial AgentsDNA, BacterialDNA GyraseDNA Mutational AnalysisDrug Resistance, BacterialDrug Therapy, CombinationEvidence-Based MedicineFluoroquinolonesGastroenterologyHelicobacter InfectionsHelicobacter pyloriHumansMicrobial Sensitivity TestsMutationProton Pump InhibitorsPyrroles1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamineAnti-Bacterial AgentsDNA, BacterialDNA GyraseFluoroquinolonesProton Pump InhibitorsPyrrolessitafloxacinSulfonamidesgyrAHelicobacter pyloriLevofloxacinMoxifloxacinSitafloxacinVonoprazan

Identifiers

PMID32351290
PMCPMC7183861

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.