Evidence map›Paper›PMID 32351289›Full record

ReviewWorld journal of gastroenterology2020

Spontaneous porto-systemic shunts in liver cirrhosis: Clinical and therapeutical aspects.

Silvia Nardelli, Oliviero Riggio, Stefania Gioia, Marta Puzzono, Giuseppe Pelle, Lorenzo Ridola

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 81 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Lumped parameter modeling of changes in liver hemodynamics due to cirrhosis.Biomechanics and modeling in mechanobiology · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
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  16. [Current status of interventional therapy for hepatic encephalopathy associated with spontaneous portosystemic shunts].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Review
  17. Review
  18. Review
  19. [The impact of spontaneous portosystemic shunt on clinical outcomes in patients with liver cirrhosis and hepatic encephalopathy].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Silvia NardelliDepartment of Translational and Precision Medicine, "Sapienza" University of Rome, Rome 00185, Italy.
Oliviero RiggioDepartment of Translational and Precision Medicine, "Sapienza" University of Rome, Rome 00185, Italy.
Stefania GioiaDepartment of Translational and Precision Medicine, "Sapienza" University of Rome, Rome 00185, Italy.
Marta PuzzonoDepartment of Translational and Precision Medicine, "Sapienza" University of Rome, Rome 00185, Italy.
Giuseppe PelleDepartment of Interventional Radiology, Santa Maria Goretti Hospital, Latina 04100, Italy.
Lorenzo RidolaDepartment of Translational and Precision Medicine, "Sapienza" University of Rome, Rome 00185, Italy. lorenzo.ridola@uniroma1.it.
Sapienza University of Rome · ITOspedale Santa Maria Goretti · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous porto-systemic shunts (SPSS) are frequent in liver cirrhosis and their prevalence increases as liver function deteriorates, probably as a consequence of worsening portal hypertension, but without achieving an effective protection against cirrhosis' complications. Several types of SPSS have been described in the literature, each one associated with different clinical manifestations. In particular, recurrent or persistent hepatic encephalopathy is more frequent in patients with splenorenal shunt, while the presence of gastric varices and consequently the incidence of variceal bleeding is more common in gastrorenal shunt. In the advanced stage, the presence of large SPSS can lead to the so called "portosystemic shunt syndrome", characterized by a progressive deterioration of hepatic function, hepatic encephalopathy and, sometimes, portal vein thrombosis. The detection of SPSS in patients with liver cirrhosis is recommended in order to prevent or treat recurrent hepatic encephalopathy or variceal bleeding.

Indexed as

Collateral CirculationEsophageal and Gastric VaricesGastrointestinal HemorrhageHepatic EncephalopathyHumansIncidenceLiverLiver CirrhosisLiver Function TestsPortal SystemSyndromeTreatment OutcomeVenous ThrombosisHepatic encephalopathyLiver cirrhosisPortal vein thrombosisPorto-systemic shuntsPorto-systemic shunt syndromeVariceal bleeding

Identifiers

PMID32351289
PMCPMC7183860
OpenAlexW3020658863

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.