Evidence map›Paper›PMID 32351149›Full record

ArticleActa oncologica (Stockholm, Sweden)2020

Predictive pharmacogenetic biomarkers for breast cancer recurrence prevention by simvastatin.

Thomas P Ahern, Per Damkier, Søren Feddersen, Anders Kjærsgaard, Timothy L Lash, Stephen Hamilton-Dutoit, Cathrine Bredal Lythjohan, Bent Ejlertsen, Peer M Christiansen, Deirdre P Cronin-Fenton

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta oncologica (Stockholm, Sweden), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Can Pharmacogenetic Variants inInternational journal of molecular sciences · 2023
    Article
  3. Simvastatin in the Treatment of Colorectal Cancer: A Review.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Thomas P AhernDepartments of Surgery and Biochemistry, Larner College of Medicine, University of Vermont, Burlington, VT, USA.
Per DamkierDepartment of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark.ORCID http://orcid.org/0000-0003-0591-7187
Søren FeddersenDepartment of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark.
Anders KjærsgaardDepartment of Clinical Epidemiology, Aarhus University Hospital/Randers Regional Hospital, Aarhus, Denmark.
Timothy L LashDepartment of Epidemiology, Rollins School of Public Health and Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Stephen Hamilton-DutoitInstitute of Pathology, Aarhus University Hospital, Aarhus, Denmark.ORCID http://orcid.org/0000-0003-2158-3885
Cathrine Bredal LythjohanInstitute of Pathology, Aarhus University Hospital, Aarhus, Denmark.
Bent EjlertsenDanish Breast Cancer Group, Rigshospitalet, Copenhagen, Denmark.
Peer M ChristiansenDanish Breast Cancer Group, Rigshospitalet, Copenhagen, Denmark.
Deirdre P Cronin-FentonDepartment of Clinical Epidemiology, Aarhus University Hospital/Randers Regional Hospital, Aarhus, Denmark.ORCID http://orcid.org/0000-0001-9738-2284
Aarhus University Hospital · DKUniversity of Southern Denmark · DKEmory University · USRigshospitalet · DKUniversity of Vermont · US

Funding

Vermont Center on Behavior and HealthP20GM103644 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI KHADANGA, SHERRIE · 2013 to 2022
$21.3M
New and integrated perspectives on modification of tamoxifen effectivenessR01CA166825 · NCI · EMORY UNIVERSITY · PI LASH, TIMOTHY L. · 2013 to 2017
$2.8M
NCI NIH HHS R01 CA166825NIGMS NIH HHS P20 GM103644
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAged, 80 and overATP Binding Cassette Transporter, Subfamily BBiomarkers, TumorBreastBreast NeoplasmsCase-Control StudiesCytochrome P-450 CYP3ADenmarkFemaleFollow-Up StudiesHumansLiver-Specific Organic Anion Transporter 1Middle AgedNeoplasm Recurrence, LocalPharmacogenomic TestingABCB1 protein, humanATP Binding Cassette Transporter, Subfamily BBiomarkers, TumorCYP3A4 protein, humanCYP3A5 protein, humanCytochrome P-450 CYP3ALiver-Specific Organic Anion Transporter 1SimvastatinSLCO1B1 protein, human

Identifiers

PMID32351149
PMCPMC7483991
OpenAlexW3022938777

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.