Evidence map›Paper›PMID 32350931›Full record

Trial reportScandinavian journal of medicine & science in sports2020

Effect of a tailored home-based exercise program in patients with systemic sclerosis: A randomized controlled trial.

Mirko Filippetti, Lucia Cazzoletti, Francesco Zamboni, Pietro Ferrari, Cristian Caimmi, Nicola Smania, Stefano Tardivo, Marcello Ferrari

Registry-linked trialOpen access · hybridAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scandinavian journal of medicine & science in sports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04922736 (Patient Reported Outcomes With UVA-1 Therapy for Treatment of Sclerosing Skin Diseases), which is not on this map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04922736 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

Patient Reported Outcomes With UVA-1 Therapy for Treatment of Sclerosing Skin Diseases

TypeinterventionalSponsorUniversity of UtahRan2021 to 2026Enrolled30ConditionsScleroderma, Systemic, Morphea, Graft Vs Host DiseaseArmsUVA-1 Phototherapy
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Review
  11. Article
  12. Review
  13. Determinants of Six-Minute Walk Test Performance in Women with Systemic Sclerosis.Journal of musculoskeletal & neuronal interactions · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mirko FilippettiUnit of Respiratory Disease and Sports Medicine, Department of Medicine, University of Verona, Verona, Italy.ORCID https://orcid.org/0000-0001-5930-5974
Lucia CazzolettiDepartment of Diagnostics and Public Health, University of Verona, Verona, Italy.
Francesco ZamboniUnit of Respiratory Disease and Sports Medicine, Department of Medicine, University of Verona, Verona, Italy.
Pietro FerrariUnit of Respiratory Disease and Sports Medicine, Department of Medicine, University of Verona, Verona, Italy.
Cristian CaimmiRheumatology Unit, Department of Medicine, University of Verona, Verona, Italy.
Nicola SmaniaNeuromotor and Cognitive Rehabilitation Research Center, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Stefano TardivoDepartment of Diagnostics and Public Health, University of Verona, Verona, Italy.
Marcello FerrariUnit of Respiratory Disease and Sports Medicine, Department of Medicine, University of Verona, Verona, Italy.
University of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim was to evaluate the effect of a home-based exercise program on functional capacity, health-related quality of life (HRQoL), and disability, in patients with systemic sclerosis (SSc).

methodsA 6-month randomized controlled trial was conducted on SSc patients by comparing a home-based minimally supervised exercise program (exercise on a stationary cycle and strengthening of upper limbs; stretching of the hands) with usual care. At baseline and after 3 and 6 months, the patients underwent: 6 minutes walking test; hand mobility in scleroderma test; maximal exercise test on an ergocycle; strength measures (handgrip, quadriceps, and biceps). HRQoL (short-form 36 [SF-36]) and disability (health assessment questionnaire disability index [HAQ-DI]) were measured at the same time.

resultsForty-four patients participated in the study. Twenty-two were randomly assigned to the intervention group (IG, mean age 63.60 ± 10.40 years) and 22 to the control group (CG, 61.80 ± 14.40 years). At 6 months, the distance walked in 6 minutes increased by 46 m (baseline 486, 95% CI 458-513 m; 6 months 532, 95% CI 504-561 m) in IG, whereas it decreased by 5 m (baseline 464, 95% CI 431-497 m; 6 months 459, 95% CI 427-490 m) in CG with a significantly different temporal trend at the between-groups comparison (P < .001). An improvement was also observed for strength measures (handgrip, P = .003; quadriceps, P < .001; biceps, P < .001), for the SF-36 physical component score (P < .001) and for the HAQ-DI (P = .011).

conclusionsThis study indicates that in SSc patients, a minimally supervised home-based exercise program improves physical performance, quality of life, and disability in comparison with usual care.

Indexed as

AgedDisability EvaluationExercise TherapyFemaleHome Care ServicesHumansMaleMiddle AgedMuscle StrengthQuality of LifeScleroderma, SystemicSurveys and QuestionnairesWalk Testdisabilityexercise therapymusclesquality of liferesistance trainingscleroderma

Identifiers

PMID32350931
PMCPMC7496851
OpenAlexW3022876592

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.