Evidence map›Paper›PMID 32350807›Full record

ArticleHead and neck pathology2020

Lymphoma Mimicking Chronic Active Epstein-Barr Virus: A Case Report.

Rohini Bahethi, Mingyang Gray, Christian Salib, Ilya Likhterov

Abstract readCase Reports
In one paragraph

Article in Head and neck pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rohini BahethiDepartment of Otolaryngology - Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, Box 1189, One Gustave L Levy Place, NY, 10029, New York, USA.ORCID http://orcid.org/0000-0002-7041-5346
Mingyang GrayDepartment of Otolaryngology - Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, Box 1189, One Gustave L Levy Place, NY, 10029, New York, USA. mingyang.gray@mountsinai.org.
Christian SalibDepartment of Pathology, Molecular & Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ilya LikhterovDepartment of Otolaryngology - Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, Box 1189, One Gustave L Levy Place, NY, 10029, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epstein-Barr virus (EBV) is the main cause of infectious mononucleosis (IM), a self-limiting infection among immunocompetent patients. EBV is also implicated in the development of several malignancies. We describe a case of a previously healthy 34-year-old man who presented with non-tender, enlarging, right cervical lymphadenopathy for over a year that was associated with significant weight loss, fevers, and night sweats. Two fine needle core biopsies showed inconclusive then reactive tissue, respectively. A third excisional biopsy demonstrated a reactive lymph node with EBV-positive IM. There was no evidence of lymphoma by histologic examination or flow cytometry. A diagnosis of chronic active EBV (CAEBV) was rendered. Subsequent lymph node debulking six months later showed classic Hodgkin lymphoma (CHL) positive for EBV. The patient underwent chemotherapy with full treatment response. This is an unusual presentation of EBV infection that led to either a delayed onset or delayed diagnosis of CHL.

Indexed as

AdultBiopsy, Fine-NeedleDiagnostic ErrorsEpstein-Barr Virus InfectionsHodgkin DiseaseHumansInfectious MononucleosisLymph NodesMale

Identifiers

PMID32350807
PMCPMC7669935

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.