ArticleFrontiers of medicine2020
Serum uric acid and risk of incident diabetes in middle-aged and elderly Chinese adults: prospective cohort study.
Article in Frontiers of medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 18 citations in OpenAlex.
- Time-restricted eating with or without low-carbohydrate diet reduces visceral fat and improves metabolic syndrome: A randomized trial.Cell reports. Medicine · 2022Trial
- Association of homocysteine and uric acid with type 2 diabetes mellitus: a case-control study.Scientific reports · 2025Article
- Identifying top ten predictors of type 2 diabetes through machine learning analysis of UK Biobank data.Scientific reports · 2024Article
- Associations of serum uric acid with cardiovascular disease risk factors: a retrospective cohort study in southeastern China.BMJ open · 2023Article
- Relationship between baseline and changed serum uric acid and the incidence of type 2 diabetes mellitus: a national cohort study.Frontiers in public health · 2023Article
- Interaction of sex and diabetes on the association between hemoglobin glycation index, hemoglobin A1c and serum uric acid.Diabetology & metabolic syndrome · 2022Article
- Association between serum uric acid with diabetes and other biochemical markers.Journal of family medicine and primary care · 2022Article
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Authors and funding
15 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association between serum uric acid and the risk of incident diabetes in Chinese adults remains unknown. This study aimed to investigate this association in a community-dwelling population aged ≥ 40 years in Shanghai, China. Oral glucose tole3rance test was conducted during baseline and follow-up visits. Relative risk regression was utilized to examine the associations between baseline gender-specific serum uric acid levels and incident diabetes risk. A total of 613 (10.3%) incident diabetes cases were identified during the follow-up visit after 4.5 years. Fasting plasma glucose, postload glucose, and glycated hemoglobin A1c during the follow-up visit progressively increased across the sex-specific quartiles of serum uric acid (all Ps < 0.05). The incidence rate of diabetes increased across the quartiles of serum uric acid (7.43%, 8.77%, 11.47%, and 13.43%). Multivariate adjusted regression analysis revealed that individuals in the highest quartile had 1.36-fold increased risk of diabetes compared with those in the lowest quartile of serum uric acid (odds ratio (95% confidence interval) = 1.36 (1.06-1.73)). Stratified analysis indicated that the association was only observed in women. Accordingly, serum uric acid was associated with the increased risk of incident diabetes among middle-aged and elderly Chinese women.
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