SynthesisTechniques in coloproctology2020
The efficacy of sacral neuromodulation in the treatment of low anterior resection syndrome: a systematic review and meta-analysis.
Synthesis in Techniques in coloproctology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 5 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Therapeutic strategies for low anterior resection syndrome: an umbrella review of systematic reviews.International journal of colorectal disease · 2025Pooled it
- The efficacy of retrograde and antegrade enemas in the management of low anterior resection syndrome in patients undergoing rectal resection: a systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- Optimal interventions for low anterior resection syndrome: Bayesian network meta-analysis of randomized controlled trials.Techniques in coloproctology · 2025Pooled it
- Systematic review of the management options available for low anterior resection syndrome (LARS).Techniques in coloproctology · 2025Pooled it
- Guideline for the diagnosis and treatment of Faecal Incontinence-A UEG/ESCP/ESNM/ESPCG collaboration.United European gastroenterology journal · 2022Guideline
- Reframing loss of efficacy in sacral neuromodulation: a neurofunctional service model for coloproctology.Techniques in coloproctology · 2026Article
- Sacral neuromodulation improves bowel function in patients with low anterior resection syndrome.Techniques in coloproctology · 2026Article
- Excitation and polarization of isolated neurons by high-frequency sine waves for temporal interference stimulation.Cell reports. Physical science · 2025Article
- From Diversion to Permanence: Trends in Ostomy Creation in Rectal Cancer Surgery.Journal of clinical medicine · 2025Review
- Article
- Differential effects of low- and high-frequency sacral neuromodulation on urinary symptoms: high-frequency improves Qmax, low-frequency enhances bladder capacity.American journal of translational research · 2025Article
- Guideline for the assessment and management of gastrointestinal symptoms following colorectal surgery-A UEG/ESCP/EAES/ESPCG/ESPEN/ESNM/ESSO collaboration. Part I-Sequelae to oncological diseases.United European gastroenterology journal · 2024Article
- Application of pelvic floor rehabilitation in patients with colorectal cancer: a scoping review.Techniques in coloproctology · 2024Article
- Long-term outcomes of sacral neuromodulation for low anterior resection syndrome after rectal cancer surgery.Annals of coloproctology · 2024Article
- Clinical Management of Low Anterior Resection Syndrome: Review of the Current Diagnosis and Treatment.Cancers · 2023Review
- Low anterior resection syndrome: An unavoidable price to pay to preserve the rectum?Frontiers in oncology · 2022Article
- A nomogram to predict risk factors of frequent defecation early after ileostomy reversal for rectal cancer patients.Annals of translational medicine · 2021Article
- [Low anterior resection syndrome-Causes and treatment approaches].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Review
- Optimising functional outcomes in rectal cancer surgery.Langenbeck's archives of surgery · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSacral neuromodulation (SNM) has become one of the main treatment options in patients with fecal incontinence. The aim of this study was to determine the efficacy of sacral neuromodulation in the treatment of low anterior resection syndrome (LARS).
methodsA systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. The search was conducted using the Pubmed, Embase, Ovid, and Cochrane databases, restricted to the English language and to articles published from 2000 to November 2018.
resultsA total of 434 articles on the efficacy of SNM in the treatment of LARS were retrieved, and 13 studies were included in the final analysis, with a total of 114 patients treated with SNM for LARS The overall success rate excluding study heterogeneity was 83.30% [95% CI (71.33-95.25%)]. Improvement in anal continence was seen in several clinical and functional parameters, including the Wexner Score [10.78 points, 95% CI (8.55-13.02), p < 0.0001], manometric maximum resting pressure [mean improvement of 6.37 mm/Hg, 95% CI (2.67-10.07), p = 0.0007], maximum squeeze pressure [mean improvement of 17.99 mm/Hg, 95% CI (17.42-18.56), p < 0.0001] and maximum tolerated volume [mean improvement of 22.74 ml, 95% CI (10.65-34.83), p = 0.0002]. Quality of life questionnaires also demonstrated significant improvement in patients' quality of life, but were reported only in a small group of included patients.
conclusionsSNM significantly improves symptoms and quality of life in patients suffering from fecal incontinence following low anterior resection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.