ArticlePediatric nephrology (Berlin, Germany)2021
Nephron number and its determinants: a 2020 update.
Article in Pediatric nephrology (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Preterm birth disrupts nephron progenitor cell dynamics predisposing to renal disease.iScience · 2026Article
- Review
- Single-cell spatial mapping of human kidney development implicates the microenvironment in guiding cell fate decisions.Nature genetics · 2026Article
- Incident Hypertension in Young Adults With a Mild Estimated Glomerular Filtration Rate Reduction.Journal of the American Heart Association · 2026Article
- Stealing nephrons-a review on how patent ductus arteriosus physiology impacts neonatal kidney health.Journal of perinatology : official journal of the California Perinatal Association · 2026Review
- Multiscale segmentation using hierarchical phase-contrast tomography and deep learning.PLoS computational biology · 2026Article
- Longitudinal trajectories of urinary albumin-to-creatinine ratio and risk of proteinuria among Chinese patients with type 2 diabetes: a single-center retrospective cohort study.Frontiers in endocrinology · 2026Article
- Innovative Technologies for Kidney Research: Three-Dimensional Imaging and Quantification.Seminars in nephrology · 2026Review
- Nephron number variability in Japanese subjects: an autopsy-based study and its implications for chronic kidney disease: clinical scientist award address 2024.Clinical and experimental nephrology · 2025Review
- Continuous increase in podocyte numbers in the first 36 months of life-insights from forensic autopsies in Japanese children.Pediatric nephrology (Berlin, Germany) · 2025Article
- Estimating Number of Nephrons in Living Pediatric Patients Using Nephrectomy Specimens.Kidney international reports · 2025Article
- Mathematical modeling reveals cell differentiation processes and progenitor kinetics necessary for proper nephrogenesis.Frontiers in cell and developmental biology · 2025Article
- Heterogeneity of absorbed dose distribution in kidney tissues and dose-response modelling of nephrotoxicity in radiopharmaceutical therapy with beta-particle emitters: A review.Zeitschrift fur medizinische Physik · 2024Review
- Two distinct phenotypes of calcium oxalate stone formers could imply different long-term risks for renal function.Urolithiasis · 2024Review
- Kidney Health Monitoring in Neonatal Intensive Care Unit Graduates: A Modified Delphi Consensus Statement.JAMA network open · 2024Article
- Two distinct phenotypes of calcium oxalate stone formers could imply different long-term risks for renal function.Research square · 2024Article
- Hypertension in children with congenital anomalies of the kidney and urinary tract.Pediatric nephrology (Berlin, Germany) · 2024Article
- Identification of a core transcriptional program driving the human renal mesenchymal-to-epithelial transition.Developmental cell · 2024Article
- Advances in pediatric acute kidney injury pathobiology: a report from the 26th Acute Disease Quality Initiative (ADQI) conference.Pediatric nephrology (Berlin, Germany) · 2024Article
- Caffeine and kidney function at two years in former extremely low gestational age neonates.Pediatric research · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Studies of human nephron number have been conducted for well over a century and have uncovered a large variability in nephron number. However, the mechanisms influencing nephron endowment and loss, along with the etiology for the wide range among individuals are largely unknown. Advances in imaging technology have allowed investigators to revisit the principles of renal structure and physiology and their roles in the progression of kidney disease. Here, we will review the latest data on the influences impacting nephron number, innovations made over the last 6 years to understand and integrate renal structure and function, and new developments in the tools used to count nephrons in vivo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.