Evidence map›Paper›PMID 32350657›Full record

ArticleEuropean radiology2020

Optimal matrix size of chest radiographs for computer-aided detection on lung nodule or mass with deep learning.

Young-Gon Kim, Sang Min Lee, Kyung Hee Lee, Ryoungwoo Jang, Joon Beom Seo, Namkug Kim

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Young-Gon KimDepartment of Biomedical Engineering, Asan Institute of Life Science, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Sang Min LeeDepartment of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43 Gil, Songpa-gu, Seoul, South Korea. sangmin.lee.md@gmail.com.
Kyung Hee LeeDepartment of Radiology, Seoul National University Bundang Hospital, Seongnam, South Korea.
Ryoungwoo JangDepartment of Biomedical Engineering, Asan Institute of Life Science, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Joon Beom SeoDepartment of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43 Gil, Songpa-gu, Seoul, South Korea.
Namkug KimDepartment of Convergence Medicine, University of Ulsan College of Medicine, Asan Medical Center, Center 88, Olympic-ro 43-gil, Seoul, South Korea. namkugkim@gmail.com.

Funding

Ministry of Trade, Industry and Energy 10072064
6 · The paper itself

Abstract

objectivesTo investigate the optimal input matrix size for deep learning-based computer-aided detection (CAD) of nodules and masses on chest radiographs.

methodsWe retrospectively collected 2088 abnormal (nodule/mass) and 352 normal chest radiographs from two institutions. Three thoracic radiologists drew 2758 abnormalities regions. A total of 1736 abnormal chest radiographs were used for training and tuning convolutional neural networks (CNNs). The remaining 352 abnormal and 352 normal chest radiographs were used as a test set. Two CNNs (Mask R-CNN and RetinaNet) were selected to validate the effects of the squared different matrix size of chest radiograph (256, 448, 896, 1344, and 1792). For comparison, figure of merit (FOM) of jackknife free-response receiver operating curve and sensitivity were obtained.

resultsIn Mask R-CNN, matrix size 896 and 1344 achieved significantly higher FOM (0.869 and 0.856, respectively) for detecting abnormalities than 256, 448, and 1792 (0.667-0.820) (p < 0.05). In RetinaNet, matrix size 896 was significantly higher FOM (0.906) than others (0.329-0.832) (p < 0.05). For sensitivity of abnormalities, there was a tendency to increase sensitivity when lesion size increases. For small nodules (< 10 mm), the sensitivities were 0.418 and 0.409, whereas the sensitivities were 0.937 and 0.956 for masses. Matrix size 896 and 1344 in Mask R-CNN and matrix size 896 in RetinaNet showed significantly higher sensitivity than others (p < 0.05).

conclusionsMatrix size 896 had the highest performance for various sizes of abnormalities using different CNNs. The optimal matrix size of chest radiograph could improve CAD performance without additional training data. KEY POINTS: • Input matrix size significantly affected the performance of a deep learning-based CAD for detection of nodules or masses on chest radiographs. • The matrix size 896 showed the best performance in two different CNN detection models. • The optimal matrix size of chest radiographs could enhance CAD performance without additional training data.

Indexed as

Deep LearningAgedDiagnosis, Computer-AssistedFemaleHumansLungLung NeoplasmsMaleMiddle AgedNeural Networks, ComputerPrecancerous ConditionsRadiographic Image Interpretation, Computer-AssistedRadiographyRadiography, ThoracicRetrospective StudiesSolitary Pulmonary NoduleAlgorithmsComputer-assisted diagnosisDeep learningLungThoracic radiography

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.