Evidence map›Paper›PMID 32350597›Full record

ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2020

Factors associated with myonecrosis at time of fasciotomy in acute leg compartment syndrome.

Dafang Zhang, Stein J Janssen, Matthew Tarabochia, Arvind von Keudell

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In one paragraph

Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Association of trauma severity scores with limb amputation and death in acute leg compartment syndrome.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2021
    Article
  3. Diabetic Myonecrosis: Lessons in Recognizing and Treating a Rare Complication.Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Dafang ZhangDepartment of Orthopaedic Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA. dzhang9@partners.org.
Stein J JanssenDepartment of Orthopaedic Surgery, Amphia Hospital, 4818CK, Breda, The Netherlands.
Matthew TarabochiaHarvard Medical School, Boston, MA, 02115, USA.
Arvind von KeudellDepartment of Orthopaedic Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA.
Harvard University · USAmphia Ziekenhuis · NLBrigham and Women's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe objective of this study is to determine factors associated with myonecrosis at the time of fasciotomy in patients with acute leg compartment syndrome.

methodsA retrospective cohort study was conducted of 546 patients with acute leg compartment syndrome treated with fasciotomies from January 2000 to June 2015 at two tertiary trauma centers. The main outcome measurement was clinical myonecrosis diagnosed by the treating surgeon at the time of fasciotomy.

resultsEighty-two patients (15.0%) with acute leg compartment syndrome had myonecrosis at time of fasciotomy. Multivariable logistic regression analyses showed that younger age (p = 0.004) and diabetes mellitus (p < 0.001) were associated with myonecrosis at time of fasciotomy in acute leg compartment syndrome. Serum creatine kinase at presentation greater than 2405 U/L was found to be associated with myonecrosis at time of fasciotomy in post hoc analysis (p < 0.001).

conclusionsMyonecrosis is associated with patient-related factors. Younger age by 10 years is associated with a 1.3 times increase and diabetes mellitus with a 3-time increase in the odds of myonecrosis. Serum creatine kinase at presentation greater than 2405 U/L denotes an almost 3 times increase in odds of myonecrosis and may be useful for preoperative counseling.

Indexed as

Compartment SyndromesFasciotomyLeg InjuriesAge FactorsCreatine KinaseDiabetes MellitusFemaleHumansIntraoperative CareMaleMiddle AgedMuscle, SkeletalNecrosisRetrospective StudiesRisk AssessmentRisk FactorsCreatine KinaseAcute compartment syndromeFasciotomyLegMyonecrosisSerum laboratory value, biomarker

Identifiers

PMID32350597
OpenAlexW3023173369

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.