Observational studyClinical infectious diseases : an official publication of the Infectious Diseases Society of America2021
Diagnosis and Treatment of Vaginal Discharge Syndromes in Community Practice Settings.
Observational study in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 43 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Diagnostic Accuracy By Providers Study
Point of Care Diagnosis of Vaginal Infections to Ensure Accurate Treatment: (PAT Study)
Who cites it
43 citing papers in PubMed, 82 citations in OpenAlex.
- Randomized Study of Usual Care Versus Xpert ® Xpress Multiplex Vaginal Panel at the Point-of-Care for Accurate Diagnosis and Appropriate Treatment of Vaginal Infections.Sexually transmitted diseases · 2026Trial
- Efficacy of Dequalinium Chloride vs Metronidazole for the Treatment of Bacterial Vaginosis: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Clinical utility of nucleic acid amplification testing for detection of sexually transmitted infections in women with symptomatic bacterial vaginosis and vulvovaginal candidiasis identified by conventional versus molecular diagnoses.Journal of clinical microbiology · 2026Article
- Comparing BD Affirm VPIII to Xpert Xpress MVP and BD MAX Vaginal Panel for the diagnosis of vaginal infections.Microbiology spectrum · 2026Article
- Vaginal Ecosystem During Gestation and Puerperium: Microbiota, Dysbiosis, Infection and Fetal-Maternal Implications.Microorganisms · 2026Review
- The Relationship of Vaginal Symptoms and Cervical Inflammation Severity with Cytological Abnormalities and HPV Positivity: A Prospective Observational Study.Biomedicines · 2026Article
- Epidemiology and management of bacterial vaginosis in Dakar, Senegal.BMC women's health · 2026Observational
- Epidemiology of vulvovaginal candidiasis in China: a six-year retrospective single-center study from a tertiary obstetrics and gynecology hospital in Shanghai.Microbiology spectrum · 2026Article
- Old but gold: an historical perspective of wet mount microscopy and its current role for the diagnosis of vaginitis.Frontiers in reproductive health · 2026Review
- Antifungal Susceptibility of Rare Yeasts Causing Vulvovaginal Candidiasis in the Acidic Vaginal Environment.Infection and drug resistance · 2026Article
- Real-World Ibrexafungerp Use Patterns Among Patients with Commercial Health Insurance, United States, 2021-2023.Drugs - real world outcomes · 2025Article
- Women presenting to emergency departments with vaginitis should be offered single-dose empirical treatment.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2025Article
- Genital cutaneous candidiasis versus chronic recurrent vulvovaginal candidiasis: distinct diseases, different populations.Clinical microbiology reviews · 2025Review
- The Prevalence of Bacterial Vaginosis in Pregnant Women in Slovenia, Determined via Microscopy and Semi-Quantitative Relative Culture, and Its Association with Adverse Pregnancy Outcomes.Microorganisms · 2025Article
- Antifungal susceptibility testing and determination of local epidemiological cut-off values forMicrobiology spectrum · 2025Article
- Mixed Vaginal Infections and Their Predictors Among Women With Abnormal Vaginal Discharges Attending Gynecological Clinics in Western Uganda: A Cross-Sectional Study.Interdisciplinary perspectives on infectious diseases · 2025Article
- Comparison of bacterial vaginosis symptoms reported in social media vs. those reported by patients.Frontiers in reproductive health · 2025Article
- Utilization of Syndromic Vaginitis Diagnostic Testing Reduces 6-Month Follow-Up Outpatient Service Healthcare Costs-A Real-World Data Analysis.Healthcare (Basel, Switzerland) · 2024Article
- Rapid Molecular Diagnostics in Vulvovaginal Candidosis.Diagnostics (Basel, Switzerland) · 2024Review
- Identifying the Impact ofPathogens (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundAlthough vaginal symptoms are common, diagnosis of bacterial vaginosis (BV), vulvovaginal candidiasis (VVC), and Trichomonas vaginalis (TV) is not standardized. Diagnostic approaches and appropriateness of treatment were evaluated for women with symptoms of vaginitis who were seeking care at community practice sites.
methodsThree hundred three symptomatic women, across 8 University of Pittsburgh Medical Center-affiliated clinics, were evaluated per standard office-based practice. Four of 5 vaginal swabs (1 cryopreserved) were collected for a US Food and Drug Administration-authorized nucleic acid amplification test (NAAT) for vaginitis/vaginosis diagnosis; Nugent scoring (BV); yeast culture (VVC); and a second NAAT (for TV). Two hundred ninety women had evaluable samples. Medical record extraction facilitated verification of treatments prescribed within 7 days of the index visit and return visit frequency within 90 days.
resultsWomen had a mean age of 29.4 ± 6.5 years, 90% were not pregnant, 79% were of white race, and 38% reported vaginitis treatment within the past month. Point-of-care tests, including vaginal pH (15%), potassium hydroxide/whiff (21%), and wet mount microscopy (17%), were rarely performed. Of the 170 women having a laboratory-diagnosed cause of vaginitis, 81 (47%) received 1 or more inappropriate prescriptions. Of the 120 women without BV, TV, or VVC, 41 (34%) were prescribed antibiotics and/or antifungals. Among women without infectious vaginitis, return visits for vaginitis symptoms were more common among women treated empirically compared to those not receiving treatment (9/41 vs 5/79, P = .02).
conclusionsWithin a community practice setting, 42% of women having vaginitis symptoms received inappropriate treatment. Women without infections who received empiric treatment were more likely have recurrent visits within 90 days. CLINICAL TRIALS REGISTRATION: NCT03151928.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.