ArticleScientific reports2020
Auranofin Rapidly Eradicates Methicillin-resistant Staphylococcus aureus (MRSA) in an Infected Pressure Ulcer Mouse Model.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 31 citations in OpenAlex.
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- Structure-Guided Semisynthesis of Blasticidin S-Amicetin Chimeras as Selective Ribosome Inhibitors.Journal of the American Chemical Society · 2026Article
- Halogenated N-(1,3,4-oxadiazol-2-yl) benzamides are effective eradicators of methicillin-resistant Staphylococcus aureus biofilms.Bioorganic & medicinal chemistry · 2026Article
- Drug Repurposing: An Emerging Strategy inJournal of microbiology and biotechnology · 2025Review
- A murine pressure ulcer model for evaluating persistence and treatment ofFrontiers in medicine · 2025Article
- Auranofin is active against Histoplasma capsulatum and reduces the expression of virulence-related genes.PLoS neglected tropical diseases · 2024Article
- Inhibition of selenoprotein synthesis is not the mechanism by which auranofin inhibits growth of Clostridioides difficile.Scientific reports · 2023Article
- Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment ofJournal of enzyme inhibition and medicinal chemistry · 2022Article
- Wound swabs versus biopsies to detect methicillin resistant Staphylococcus aureus in experimental equine wounds.Veterinary surgery : VS · 2022Article
- Mechanistic Studies andJournal of medicinal chemistry · 2022Article
- Comparative Studies to Uncover Mechanisms of Action ofACS infectious diseases · 2022Article
- In vivo efficacy of acetazolamide in a mouse model of Neisseria gonorrhoeae infection.Microbial pathogenesis · 2022Article
- Synergistic Microbicidal Effect of AUR and PEITC AgainstFrontiers in cellular and infection microbiology · 2022Article
- Auranofin exerts antibacterial activity against Neisseria gonorrhoeae in a female mouse model of genital tract infection.PloS one · 2022Article
- Repurposing of auranofin and honokiol as antifungals againstVirulence · 2021Article
- Investigating auranofin for the treatment of infected diabetic pressure ulcers in mice and dermal toxicity in pigs.Scientific reports · 2021Article
- Total synthesis of landomycins Q and R and related core structures for exploration of the cytotoxicity and antibacterial properties.RSC advances · 2021Article
- Article
- Thioredoxin Reductase Is a Valid Target for Antimicrobial Therapeutic Development Against Gram-Positive Bacteria.Frontiers in microbiology · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Pressure ulcers (PUs) frequently occur in individuals with limited mobility including patients that are hospitalized or obese. PUs are challenging to resolve when infected by antibiotic-resistant bacteria, particularly methicillin-resistant Staphylococcus aureus (MRSA). In this study, we investigated the potential of repurposing auranofin to treat pressure ulcers infected with MRSA. Auranofin's in vitro activity against strains of S. aureus (including MRSA) was not affected in the presence of higher bacterial inoculum (10
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