Evidence map›Paper›PMID 32350237›Full record

ReviewMedical science monitor : international medical journal of experimental and clinical research2020

Research Progress of N6-Methyladenosine in the Cardiovascular System.

Nan Zheng, Jia Su, Haochang Hu, Jingqiao Wang, Xiaomin Chen

Open access · hybridAbstract readReview
In one paragraph

Review in Medical science monitor : international medical journal of experimental and clinical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Epitranscriptomics of cardiovascular diseases (Review).International journal of molecular medicine · 2022
    Review
  5. Review
  6. Genetic drivers of mNature genetics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nan ZhengDepartment of Cardiovascular Medicine, Ningbo Hospital of Zhejiang University, Ningbo, Zhejiang, China (mainland).
Jia SuDepartment of Cardiovascular Medicine, Ningbo Hospital of Zhejiang University, Ningbo, Zhejiang, China (mainland).
Haochang HuDepartment of Cardiovascular Medicine, Ningbo Hospital of Zhejiang University, Ningbo, Zhejiang, China (mainland).
Jingqiao WangDepartment of Cardiovascular Medicine, Ningbo Hospital of Zhejiang University, Ningbo, Zhejiang, China (mainland).
Xiaomin ChenDepartment of Cardiovascular Medicine, Ningbo Hospital of Zhejiang University, Ningbo, Zhejiang, China (mainland).
Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the World Health Organization cardiovascular disease risk charts, the mortality rate of cardiovascular diseases in people is still high. The medical expenses caused by cardiovascular diseases are increasing daily, and the medical burden is becoming heavier; as such, it is imperative to prevent and cure cardiovascular diseases. A large number of scholars are analyzing the pathogenesis of cardiovascular diseases from various perspectives. Recent findings suggest that N6-methyladenosine (m6A) plays a multifaceted role in the cardiovascular system. m6A is a methylated modification product on RNA molecules and exists on various RNA molecules. It is one of the most common epigenetic modifications discovered to date. It regulates the expression of genes and subsequent responses. The amount of m6A is determined by methylases (writers) and demethylases (erasers). The third type of proteins, readers, selectively bind to m6A to regulate RNA stability and gene expression. In this paper, the relationship between m6A and related enzymes and cardiovascular structure and function was reviewed based on recent research results regarding the cardiovascular system.

Indexed as

AdenosineCardiovascular DiseasesCardiovascular SystemEpigenesis, GeneticGene ExpressionHumansLipid MetabolismLipidsMethylationMethyltransferasesAdenosineLipidsMethyltransferasesN-methyladenosine

Identifiers

PMID32350237
PMCPMC7207004
OpenAlexW3020896579

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.