Evidence map›Paper›PMID 32350096›Full record

ArticlemSphere2020

Disruption of Cross-Feeding Inhibits Pathogen Growth in the Sputa of Patients with Cystic Fibrosis.

Jeffrey M Flynn, Lydia C Cameron, Talia D Wiggen, Jordan M Dunitz, William R Harcombe, Ryan C Hunter

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Observational
  11. We have a community problem.Journal of bacteriology · 2024
    Article
  12. Article
  13. Co-occurring microflora and mucin driveISME communications · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jeffrey M FlynnDepartment of Microbiology & Immunology, University of Minnesota, Minneapolis, Minnesota, USA.
Lydia C CameronDepartment of Microbiology & Immunology, University of Minnesota, Minneapolis, Minnesota, USA.
Talia D WiggenDepartment of Microbiology & Immunology, University of Minnesota, Minneapolis, Minnesota, USA.
Jordan M DunitzDivision of Pulmonary, Allergy, Critical Care, & Sleep Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
William R HarcombeDepartment of Ecology, Evolution, and Behavior, University of Minnesota, Saint Paul, Minnesota, USA.ORCID 0000-0001-8445-2052
Ryan C HunterDepartment of Microbiology & Immunology, University of Minnesota, Minneapolis, Minnesota, USA rchunter@umn.edu.ORCID 0000-0003-3841-1676
University of Minnesota · US

Funding

Bacterial mucin degradation in cystic fibrosis airway disease.R01HL136919 · NHLBI · UNIVERSITY OF MINNESOTA · PI HUNTER, RYAN COULSON · 2017 to 2021
$2.1M
NHLBI NIH HHS R01 HL136919
6 · The paper itself

Abstract

A critical limitation in the management of chronic polymicrobial infections is the lack of correlation between antibiotic susceptibility testing (AST) and patient responses to therapy. Underlying this disconnect is our inability to accurately recapitulate the

Indexed as

Microbial InteractionsAnti-Bacterial AgentsBacteria, AnaerobicCoinfectionCystic FibrosisDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsMicrobiotaMucinsPseudomonas aeruginosaSputumAnti-Bacterial AgentsMucinsantibioticscross-feedingcystic fibrosisPseudomonas aeruginosa

Identifiers

PMID32350096
PMCPMC7193046
OpenAlexW3021687028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.