Evidence map›Paper›PMID 32349835›Full record

ArticleEuropean psychiatry : the journal of the Association of European Psychiatrists2020

Improving social function with real-world social-cognitive remediation in schizophrenia: Results from the RemedRugby quasi-experimental trial.

Julien Dubreucq, Franck Gabayet, Bernard Ycart, Megane Faraldo, Fanny Melis, Thierry Lucas, Benjamin Arnaud, Mickael Bacconnier, Motassem Bakri, Gentiane Cambier and 15 more

Abstract readControlled Clinical Trial
In one paragraph

Article in European psychiatry : the journal of the Association of European Psychiatrists, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Aerobic exercise in severe mental illness: requirements from the perspective of sports medicine.European archives of psychiatry and clinical neuroscience · 2022
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Julien DubreucqCentre de Neurosciences Cognitive, UMR 5229, CNRS and Université Lyon 1, Lyon, France.ORCID 0000-0003-4079-4194
Franck GabayetCentre Référent de Réhabilitation Psychosociale et de Remédiation cognitive (C3R), Centre Hospitalier Alpes Isère, Grenoble, France.ORCID 0000-0002-0585-0456
Bernard YcartLaboratoire Jean Kuntzmann, CNRS UMR 5224, Université Grenoble-Alpes, Grenoble, France.
Megane FaraldoCentre Référent de Réhabilitation Psychosociale et de Remédiation cognitive (C3R), Centre Hospitalier Alpes Isère, Grenoble, France.ORCID 0000-0002-2021-2049
Fanny MelisCentre Référent de Réhabilitation Psychosociale et de Remédiation cognitive (C3R), Centre Hospitalier Alpes Isère, Grenoble, France.
Thierry LucasCentre Référent de Réhabilitation Psychosociale et de Remédiation cognitive (C3R), Centre Hospitalier Alpes Isère, Grenoble, France.
Benjamin ArnaudCentre Hospitalier Sainte Marie de Clermont Ferrand, 33 rue Gabriel Péri, CS 9912, Clermont-Ferrand Cedex 1 63037, France.
Mickael BacconnierCentre Médical La Teppe, 25 Avenue de la Bouterne, CS 9721, Tain-l'Hermitage Cedex 26602, France.
Motassem BakriCentre de Réhabilitation Psychosociale et de Remédiation Cognitive (C2R), CH Drôme Vivarais, Montéléger, France.
Gentiane CambierCentre Hospitalier de la Savoie, 89 avenue de Bassens, Bassens73000, France.
Florian CarmonaREHALise, CHU de Saint-Etienne, Saint-Etienne, France.
Isabelle ChereauFondation FondaMental, Créteil, France.
Titaua ChalleCentre Départemental de Réhabilitation Psychosociale des Glières, 219 Chemin des Bois des Fornets, La Roche sur Foron 74800, France.
Sophie MorelCentre de Réhabilitation Psychosociale et de Remédiation Cognitive (C2R), CH Drôme Vivarais, Montéléger, France.
Sylvie PiresFondation FondaMental, Créteil, France.
Celine RousselCentre Départemental de Réhabilitation Psychosociale des Glières, 219 Chemin des Bois des Fornets, La Roche sur Foron 74800, France.
Philippe LamyREHALise, CHU de Saint-Etienne, Saint-Etienne, France.
Guillaume LegrandCentre Hospitalier Sainte Marie de Clermont Ferrand, 33 rue Gabriel Péri, CS 9912, Clermont-Ferrand Cedex 1 63037, France.
Emmanuelle PagesCentre Hospitalier de la Savoie, 89 avenue de Bassens, Bassens73000, France.
Romain PommierREHALise, CHU de Saint-Etienne, Saint-Etienne, France.
Romain ReyFondation FondaMental, Créteil, France.
Yohan SouchetFondation FondaMental, Créteil, France.
Pierre-Michel LlorcaFondation FondaMental, Créteil, France.
Catherine MassoubreREHALise, CHU de Saint-Etienne, Saint-Etienne, France.
RemedRugby Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional capacity (FC) has been identified as a key outcome to improve real-world functioning in schizophrenia. FC is influenced by cognitive impairments, negative symptoms, self-stigma and reduced physical activity (PA). Psychosocial interventions targeting FC are still under-developed.

methodswe conducted a quasi-experimental study evaluating the effects of an exercise-enriched integrated social cognitive remediation (SCR) intervention (RemedRugby [RR]) compared with an active control group practicing Touch Rugby (TR). To our knowledge, this is the first trial to date evaluating the effectiveness of such a program provided in a real-life environment.

resultsEighty-seven people with schizophrenia were included and allocated to either the RR group (n = 57) or the TR group (n = 30) according to the routine clinical practice of the recruiting center. Outcomes were evaluated at baseline and post-treatment in both groups and after 6 months of follow-up in the RR group using standardized scales for symptom severity, social functioning, self-stigma, and a large cognitive battery. After treatment we observed moderate to large improvements in social function (Personal and Social Performance Scale [PSP], p < 0.001, d = 1.255), symptom severity (Positive and Negative Syndrome Scale [PANSS] negative, p < 0.001, d = 0.827; PANSS GP, p < 0.001, d = 0.991; PANSS positive, p = 0.009, d = 0.594), verbal abstraction (p = 0.008, d = 0.554), aggression bias (p = 0.008, d = 0.627), and self-stigma (stereotype endorsement, p = 0.019, d = 0.495; discrimination experiences, p = 0.047; d = 0.389) that were specific to the RR group and were not observed in participants playing only TR. Effects were persistent over time and even larger between post-treatment and follow-up.

conclusionsExercise-enriched integrated SCR appears promising to improve real-life functioning in schizophrenia. Future research should investigate the potential effects of this intervention on neuroplasticity and physical fitness.

Indexed as

Exercise TherapySocial BehaviorSocial SkillsAdultCognitive RemediationCombined Modality TherapyFemaleFollow-Up StudiesHumansMaleSchizophreniaPhysical activityschizophreniasocial cognitive remediationsocial functiontouchrugby

Identifiers

PMID32349835
PMCPMC7355162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.