Evidence map›Paper›PMID 32349795›Full record

ArticleJournal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale2020

Bacterial aetiology of chronic otitis media with effusion in children - risk factors.

Izabela Korona-Glowniak, Agata Wisniewska, Marek Juda, Karolina Kielbik, Grazyna Niedzielska, Anna Malm

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Article
  3. Does Helicobacter pylori have a role in the pathogenesis of otitis media with effusion, or is it a fallacy??European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Izabela Korona-GlowniakDepartment of Pharmaceutical Microbiology, Medical University of Lublin, 1 W. Chodzki Str, 20-093, Lublin, Poland. iza.glowniak@umlub.pl.ORCID http://orcid.org/0000-0003-1634-0387
Agata WisniewskaDepartment of Pediatric Otolaryngology, Phoniatrics and Audiology, Medical University of Lublin, 6 Prof. A. Gebali Str, 20-093, Lublin, Poland.
Marek JudaDepartment of Pharmaceutical Microbiology, Medical University of Lublin, 1 W. Chodzki Str, 20-093, Lublin, Poland.
Karolina KielbikDepartment of Pharmaceutical Microbiology, Medical University of Lublin, 1 W. Chodzki Str, 20-093, Lublin, Poland.
Grazyna NiedzielskaDepartment of Pediatric Otolaryngology, Phoniatrics and Audiology, Medical University of Lublin, 6 Prof. A. Gebali Str, 20-093, Lublin, Poland.
Anna MalmDepartment of Pharmaceutical Microbiology, Medical University of Lublin, 1 W. Chodzki Str, 20-093, Lublin, Poland.
Medical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOtitis media with effusion (OME) may occur spontaneously because of poor Eustachian tube function or as an inflammatory response following AOM. Bacterial involvement in OME has been widely reported, with various available methods to identify pathogens from middle ear effusion, including traditional culture methods and polymerase chain reaction (PCR).

objectivesThe primary goal of this study was to evaluate the bacteriological profile of middle ear effusion in OME. Risk factors of the bacterial OME aetiology were also identified.

methodsMiddle ear effusions (MEF) from 50 children, aged 2-8 years, diagnosed by ENT and undergoing routine tympanostomy tube placement were collected. MEF samples were streaked on standard microbiological media. Next, DNA was isolated from MEF samples and analysed with multiplex PCR for Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Alloiococcus otitidis.

resultsIn multiplex PCR assay 37 (74%) of 50 children were positive for at least one of the four microorganisms. In 27.0% positive children multiple bacterial pathogens were identified. A. otitidis was the most frequently identified in positive MEF children (59.5%). By multiplex PCR, H. influenzae, S. pneumoniae and M. catarrhalis were detected in 24, 18 and 8% of OME patients, respectively. There was significant association between bilateral infection and H. influenzae aetiology of OME.

conclusionsOverall we found OME predominantly a single otopathogen infection caused mainly by A. otitidis, which is difficult in identification using standard culture method, ahead to S. pneumoniae and H. influenzae. However, one third of MEF samples had multiple bacterial pathogens.

Indexed as

BacteriaCarnobacteriaceaeChildChild, PreschoolChronic DiseaseFemaleHaemophilus influenzaeHumansMaleMoraxella catarrhalisOtitis Media with EffusionPolymerase Chain ReactionProspective StudiesRisk FactorsStreptococcus pneumoniaeOtitis media with effusionOtopathogensRisk factors

Identifiers

PMID32349795
PMCPMC7191732
OpenAlexW3022745209

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.