Evidence map›Paper›PMID 32349638›Full record

ArticleThe Journal of orthopaedic and sports physical therapy2020

Local Anesthetic Injection Resolves Movement Pain, Motor Dysfunction, and Pain Catastrophizing in Individuals With Chronic Achilles Tendinopathy: A Nonrandomized Clinical Trial.

Ruth L Chimenti, Mederic M Hall, Connor P Dilger, Ericka N Merriwether, Jason M Wilken, Kathleen A Sluka

Open access · greenAbstract readControlled Clinical Trial
In one paragraph

Article in The Journal of orthopaedic and sports physical therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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  13. What Do We Know about Nociplastic Pain?Healthcare (Basel, Switzerland) · 2023
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  18. Effects of kinesiophobia and pain on performance and willingness to perform jumping tests in Achilles tendinopathy: A cross-sectional study.Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ruth L Chimenti
Mederic M Hall
Connor P Dilger
Ericka N Merriwether
Jason M Wilken
Kathleen A Sluka
New York University · USUniversity of Iowa · US

Funding

University of Iowa Institute for Clinical and Translational ScienceU54TR001013 · NCATS · UNIVERSITY OF IOWA · PI ROSENTHAL, GARY E · 2014 to 2014
$4.2M
Interdisciplinary Training Program in Pain ResearchT32NS045549 · NINDS · UNIVERSITY OF IOWA · PI KATHLEEN A SLUKA, Yuriy M Usachev · 2004 to 2026
$3.7M
Mechanism-based treatment approach to chronic tendinopathy painK99AR071517 · NIAMS · UNIVERSITY OF IOWA · PI CHIMENTI, RUTH LOUISE PORTER · 2017 to 2018
$172k
NCATS NIH HHS U54 TR001013NIAMS NIH HHS K99 AR071517NINDS NIH HHS T32 NS045549
6 · The paper itself

Abstract

objectivesPeripherally directed treatments (targeted exercise, surgery) can reduce, but not fully eliminate, pain for up to 40% of patients with Achilles tendinopathy. The objectives of the present study were (1) to identify indicators of altered central processing in participants with Achilles tendinopathy compared to controls, and (2) to determine which indicators of altered central processing would persist after a local anesthetic injection in patients with Achilles tendinopathy.

designMechanistic clinical trial.

methodsForty-six adults (23 with chronic Achilles tendinopathy, 23 matched controls) repeated (1) a movement-evoked pain rating, (2) motor performance assessment, (3) pain psychology questionnaires, and (4) quantitative sensory testing. Participants with Achilles tendinopathy received a local anesthetic injection before repeat testing and controls did not. Mixed-effects analyses of variance examined the effects of group, time, and group by time.

resultsThe Achilles tendinopathy group had movement-evoked pain, motor dysfunction, and higher pain psychological factors (pain catastrophizing, kinesiophobia) compared to controls (

conclusionPeople with Achilles tendinopathy had elevated pain psychological factors and motor dysfunction but no signs of nociplastic pain with quantitative sensory testing. Removal of nociceptive input normalized movement-evoked pain and some indicators of altered central processing (motor dysfunction, pain catastrophizing), but not kinesiophobia.

Indexed as

Achilles TendonCatastrophizationAdultAnesthetics, LocalChronic DiseaseFemaleHumansMaleMiddle AgedMovementNociceptive PainRopivacaineTendinopathyUltrasonographyAnesthetics, LocalRopivacainecentral sensitizationkinesiophobiakineticsmovement-evoked painnociceptive

Identifiers

PMID32349638
PMCPMC10016231
OpenAlexW3021553957

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.