Evidence map›Paper›PMID 32349586›Full record

ArticleJournal of the American Heart Association2020

Prenatal and Postnatal Cardiac Development in Offspring of Hypertensive Pregnancies.

Christina Y L Aye, Adam J Lewandowski, Pablo Lamata, Ross Upton, Esther Davis, Eric O Ohuma, Yvonne Kenworthy, Henry Boardman, Annabelle L Frost, Satish Adwani and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  3. Trial
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  5. Article
  6. Cardiac morphology and flow dynamics in children born to hypertensive pregnancies.European heart journal. Imaging methods and practice · 2026
    Article
  7. Fetal cardiac remodeling in second trimester in pregnancies with pre-eclampsia and/or fetal growth restriction: deep-learning-based approach using population-wide data.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026
    Article
  8. Angiogenic Biomarkers and Neonatal Outcomes in Suspected Preeclampsia: Retrospective Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2026
    Article
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  18. Preeclampsia and Cardiovascular Risk for Offspring.Journal of clinical medicine · 2021
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Christina Y L AyeDivision of Cardiovascular Medicine Oxford Cardiovascular Clinical Research Facility Oxford United Kingdom.
Adam J LewandowskiDivision of Cardiovascular Medicine Oxford Cardiovascular Clinical Research Facility Oxford United Kingdom.
Pablo LamataDepartment of Biomedical Engineering King's College London London United Kingdom.
Ross UptonDivision of Cardiovascular Medicine Oxford Cardiovascular Clinical Research Facility Oxford United Kingdom.
Esther DavisDivision of Cardiovascular Medicine Oxford Cardiovascular Clinical Research Facility Oxford United Kingdom.
Eric O OhumaNuffield Department of Medicine Centre for Tropical Medicine and Global Health University of Oxford United Kingdom.
Yvonne KenworthyDivision of Cardiovascular Medicine Oxford Cardiovascular Clinical Research Facility Oxford United Kingdom.
Henry BoardmanDivision of Cardiovascular Medicine Oxford Cardiovascular Clinical Research Facility Oxford United Kingdom.
Annabelle L FrostDivision of Cardiovascular Medicine Oxford Cardiovascular Clinical Research Facility Oxford United Kingdom.
Satish AdwaniDepartment of Paediatrics and Neonatology John Radcliffe Hospital Oxford United Kingdom.
Kenny McCormick
Paul LeesonDivision of Cardiovascular Medicine Oxford Cardiovascular Clinical Research Facility Oxford United Kingdom.
Angkor Hospital for Children · KHJohn Radcliffe Hospital · GBKing's College London · GBMcCormick (United States) · USUniversity of Oxford · GB

Funding

British Heart Foundation FS/11/65/28865British Heart Foundation FS/18/3/33292Department of HealthWellcome TrustWellcome Trust 209450/Z/17/Z
6 · The paper itself

Abstract

Background Pregnancy complications such as preterm birth and fetal growth restriction are associated with altered prenatal and postnatal cardiac development. We studied whether there were changes related specifically to pregnancy hypertension. Methods and Results Left and right ventricular volumes, mass, and function were assessed at birth and 3 months of age by echocardiography in 134 term-born infants. Fifty-four had been born to mothers who had normotensive pregnancy and 80 had a diagnosis of preeclampsia or pregnancy-induced hypertension. Differences between groups were interpreted, taking into account severity of pregnancy disorder, sex, body size, and blood pressure. Left and right ventricular mass indexed to body surface area (LVMI and RVMI) were similar in both groups at birth (LVMI 20.9±3.7 versus 20.6±4.0 g/m

Indexed as

Blood PressurePrenatal Exposure Delayed EffectsAdultAge FactorsCase-Control StudiesChild DevelopmentFemaleHeartHeart DiseasesHumansHypertension, Pregnancy-InducedInfantInfant, NewbornMalePregnancyProspective Studieshigh blood pressurehypertensionpreeclampsiapregnancyventricular

Identifiers

PMID32349586
PMCPMC7428573
OpenAlexW3013404150

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.