Evidence map›Paper›PMID 32349538›Full record

SynthesisCephalalgia : an international journal of headache2020

Dizziness and vertigo during the prodromal phase and headache phase of migraine: A systematic review and meta-analysis.

Afrim Iljazi, Håkan Ashina, Richard B Lipton, Basit Chaudhry, Haidar M Al-Khazali, James G Naples, Henrik W Schytz, Vlasta Vukovic Cvetkovic, Rami Burstein, Sait Ashina

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Cephalalgia : an international journal of headache, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Focused Update on Migraine and Vertigo Comorbidity.Current pain and headache reports · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Cerebro-Cerebellar Networks in Migraine Symptoms and Headache.Frontiers in pain research (Lausanne, Switzerland) · 2022
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Afrim IljaziDanish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Håkan AshinaDanish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Richard B LiptonMontefiore Headache Center, Department of Neurology, Albert Einstein College of Medicine, New York, NY, USA.
Basit ChaudhryDanish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Haidar M Al-KhazaliDanish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
James G NaplesDepartment of Otolaryngology-Head and Neck Surgery, Otology, Neurotology, and Skull Base Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Henrik W SchytzDanish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Vlasta Vukovic CvetkovicDanish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Rami BursteinBIDMC Comprehensive Headache Center, Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Sait AshinaBIDMC Comprehensive Headache Center, Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Beth Israel Deaconess Medical Center · USGlostrup Hospital · DKHarvard University · USUniversity of Copenhagen · DKAlbert Einstein College of Medicine · USRigshospitalet · DK

Funding

Vascular Structure and Function in Cognitive AgingP01AG003949 · NIA · YESHIVA UNIVERSITY · PI CAROL A. DERBY · 1985 to 2026
$73.9M
MRI Measures of Cerebrovascular Injury and AD Atrophy in a Study of LatinosRF1AG054548 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DECARLI, CHARLES, GONZALEZ, HECTOR M · 2017 to 2017
$14.7M
Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA)R01AG048642 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GONZALEZ, HECTOR M · 2015 to 2019
$5.7M
Brain injury due to soccer heading and opportunities for its mitigationR01NS082432 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI LIPTON, MICHAEL LAWRENCE · 2013 to 2017
$3.5M
Photophobia during migraine: sensory, autonomic and emotional responses to lightR37NS079678 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BURSTEIN, RAMI · 2012 to 2018
$3.1M
COSMIC: An international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethno-racial groups and geographical settingsRF1AG057531 · NIA · UNIVERSITY OF NEW SOUTH WALES · PI SACHDEV, PERMINDER S · 2017 to 2020
$2.9M
Einstein Center for Excellence for Clinical Trials in NeuroscienceU10NS077308 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI LIPTON, RICHARD B., SHINNAR, SHLOMO · 2011 to 2017
$2.2M
Cortical Mechanisms of Headache: Beyond CSDR01NS094198 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BURSTEIN, RAMI · 2016 to 2020
$1.9M
The biological underpinnings of Motoric Cognitive Risk syndrome: a multi-center studyR56AG057548 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI VERGHESE, JOE · 2017 to 2017
$1.2M
The relation of migraine to daily hormone patterns and menopausal stageK23AG049466 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI PAVLOVIC, JELENA · 2016 to 2021
$918k
Application of latent and integrative approaches to understand the spectrum of cognitive agingK01AG054700 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI ZAMMIT, ANDREA ROSE · 2017 to 2021
$653k
NIA NIH HHS K01 AG054700NIA NIH HHS K23 AG049466NIA NIH HHS P01 AG003949NIA NIH HHS R01 AG048642NIA NIH HHS R56 AG057548NIA NIH HHS RF1 AG054548NIA NIH HHS RF1 AG057531NINDS NIH HHS R01 NS082432NINDS NIH HHS R01 NS094198NINDS NIH HHS R37 NS079678NINDS NIH HHS U10 NS077308
6 · The paper itself

Abstract

objectiveTo assess the proportion of individuals who report dizziness and/or vertigo during the prodromal phase or headache phase of migraine.

methodsThe databases of MEDLINE and EMBASE were searched for studies on dizziness and/or vertigo during the prodromal phase or headache phase of migraine. Pooled relative frequencies were estimated using a random-effects meta-analysis.

resultsWe identified nine articles eligible for inclusion. Of these, one study reported results for the prodromal phase, seven studies for the headache phase and one study for both the prodromal and headache phase. In the prodromal phase, 9.0% of individuals with migraine reported dizziness, while 3.3% reported vertigo. During the headache phase, relative frequency of dizziness ranged from 6.7% to 59.6%, while vertigo ranged from 6.4% to 44.7%. The meta-analysis showed a relative frequency of 35.7% for dizziness (95% CI = 13.7-61.5%, I

conclusionWe found that there is a scarcity of literature on dizziness and vertigo as prodromal- and headache-associated symptoms in individuals with migraine. Methodological variations confound comparisons of epidemiological patterns, although it appears that dizziness and vertigo are more frequent during the headache phase of migraine, compared with the prodromal phase. Future studies should ensure use of standardized definitions and rigorous methodology to enable accurate measurements of dizziness and vertigo in migraine.

Indexed as

Prodromal SymptomsDizzinessHumansMigraine DisordersVertigoassociated symptomsclassificationEpidemiologyvestibular migrainevestibular symptoms

Identifiers

PMID32349538
PMCPMC7483950
OpenAlexW3021697601

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.