ArticleMembranes2020
Precipitation of Inorganic Salts in Mitochondrial Matrix.
Article in Membranes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Primary cortical neurons precipitate and extrude large mitochondria-associated calcium-phosphate sheets with a bone-precursor-like ultrastructure.Molecular brain · 2026Article
- Modulation of Mesangial Cells by Tamsulosin and Pioglitazone Under Hyperglycemic Conditions: An In Vitro and In Vivo Study.International journal of molecular sciences · 2025Article
- Primary cortical neurons precipitate and extrude large mitochondria-associated calcium-phosphate sheets with a bone-precursor-like ultrastructure.bioRxiv : the preprint server for biology · 2025Article
- Article
- Energy optimisation predicts the capacity of ion buffering in the brain.Biological cybernetics · 2023Article
- Mitochondrial ion channels in cardiac function.American journal of physiology. Cell physiology · 2021Review
- Article
- Mitochondrial Calcification.Immunometabolism · 2021Article
- Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
In the mitochondrial matrix there are insoluble, osmotically inactive complexes that maintain constant pH and calcium concentration. In the present paper we examine the properties of insoluble calcium and magnesium salts, namely phosphates, carbonates and polyphosphates which might play this role. We find that non-stoichiometric, magnesium-rich carbonated apatite, with very low crystallinity, precipitates in the matrix under physiological conditions. Precipitated salt acts as pH buffer, and hence can contribute in maintaining ATP production in ischemic conditions, delaying irreversible damages to heart and brain cells after stroke.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.