Evidence map›Paper›PMID 32349386›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Endometrial Cancer Risk Prediction According to Indication of Diagnostic Hysteroscopy in Post-Menopausal Women.

Carlo Saccardi, Amerigo Vitagliano, Matteo Marchetti, Alice Lo Turco, Sofia Tosatto, Michela Palumbo, Luciana Serena De Lorenzo, Salvatore Giovanni Vitale, Marco Scioscia, Marco Noventa

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06125886 (A Multicenter Clinical Study on Endometrial Cancer Screening in High-risk Populations in China), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06125886 naunknown statusnot on this mapstarted 2023, after this paper: background citation

A Multicenter Clinical Study on Endometrial Cancer Screening in High-risk Populations in China

TypeinterventionalSponsorPeking University People's HospitalRan2023 to 2025Enrolled22,000ConditionsCancer ScreeningArmstransvaginal ultrasound and microscale endometrial sampling biopsy
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Recent Multiomics Approaches in Endometrial Cancer.International journal of molecular sciences · 2022
    Review
  12. Review
  13. Article
  14. Evaluation of menopausal endometrial lesions via mathematical modeling clinical indicators and ultrasonographic parameters.Technology and health care : official journal of the European Society for Engineering and Medicine · 2022
    Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Carlo SaccardiDepartment of Women's and Children's Health, University of Padua, 35100 Padua, Italy.
Amerigo VitaglianoDepartment of Women's and Children's Health, University of Padua, 35100 Padua, Italy.
Matteo MarchettiDepartment of Women's and Children's Health, University of Padua, 35100 Padua, Italy.
Alice Lo TurcoDepartment of Women's and Children's Health, University of Padua, 35100 Padua, Italy.
Sofia TosattoDepartment of Women's and Children's Health, University of Padua, 35100 Padua, Italy.
Michela PalumboDepartment of Women's and Children's Health, University of Padua, 35100 Padua, Italy.ORCID 0000-0003-1207-2872
Luciana Serena De LorenzoDepartment of Women's and Children's Health, University of Padua, 35100 Padua, Italy.
Salvatore Giovanni VitaleDepartment of General Surgery and Medical Surgical Specialties, University of Catania, 95124 Catania, Italy.ORCID 0000-0001-6871-6097
Marco SciosciaDepartment of Obstetrics and Gynecology, Policlinico Abano Terme, 35031, Italy.ORCID 0000-0002-5757-2793
Marco NoventaDepartment of Women's and Children's Health, University of Padua, 35100 Padua, Italy.
University of Padua · ITPoliclinico Abano Terme · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted a prospective observational study investigating the clinical relevance of endometrial thickness (ET) and abnormal uterine bleeding (AUB) on endometrial cancer (EC) risk in a cohort of postmenopausal patients undergoing diagnostic hysteroscopy and endometrial biopsy. Patients were divided into two groups according to the indication of diagnostic hysteroscopy: ET_Group (asymptomatic patients with endometrial thickness ≥ 4 mm) and AUB_Group (patients with a history of abnormal uterine bleeding). We further divided the AUB_Group into two subgroups based on endometrial thickness (AUB_Subgroup1: ET < 4 mm; AUB_Subgroup2: ET ≥ 4 mm). The primary outcome was the risk of endometrial cancer and atypical hyperplasia according to the indications of diagnostic hysteroscopy (AUB, ET ≥ 4 mm or both). The secondary outcome was to determine the best cut-off value of endometrial thickness to predict endometrial cancer in asymptomatic postmenopausal women. The prevalence of endometrial cancer and atypical hyperplasia in AUB_Group and ET_Group was 21% and 6.7% respectively. As well as for EC alone, higher prevalence of both conditions was observed in AUB_Subgroup2 (29.3%) in comparison to AUB_Subgroup1 (10.6%;

Indexed as

asymptomatic womenAUBdiagnostic hysteroscopyearly diagnosisendometrial cancerendometrial thicknessmenopause

Identifiers

PMID32349386
PMCPMC7277718
OpenAlexW3018937158

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.