Evidence map›Paper›PMID 32349337›Full record

ReviewInternational journal of molecular sciences2020

Role of the Furosemide Stress Test in Renal Injury Prognosis.

Armando Coca, Carmen Aller, Jimmy Reinaldo Sánchez, Ana Lucía Valencia, Elena Bustamante-Munguira, Juan Bustamante-Munguira

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Understanding Renal Tubular Function: Key Mechanisms, Clinical Relevance, and Comprehensive Urine Assessment.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Editorial for Special Issue-Biomarkers of Renal Disease.International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Armando CocaDepartment of Nephrology, Hospital Clinico Universitario de Valladolid, 47003 Valladolid, Spain.ORCID 0000-0002-1724-5229
Carmen AllerDepartment of Nephrology, Hospital Clinico Universitario de Valladolid, 47003 Valladolid, Spain.
Jimmy Reinaldo SánchezDepartment of Nephrology, Hospital Clinico Universitario de Valladolid, 47003 Valladolid, Spain.
Ana Lucía ValenciaDepartment of Nephrology, Hospital Clinico Universitario de Valladolid, 47003 Valladolid, Spain.
Elena Bustamante-MunguiraDepartment of Intensive Care Medicine, Hospital Clinico Universitario de Valladolid, 47003 Valladolid, Spain.
Juan Bustamante-MunguiraDepartment of Cardiac Surgery, Hospital Clinico Universitario de Valladolid, 47003 Valladolid, Spain.ORCID 0000-0002-6542-4504

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Risk stratification and accurate patient prognosis are pending issues in the management of patients with kidney disease. The furosemide stress test (FST) has been proposed as a low-cost, fast, safe, and easy-to-perform test to assess tubular integrity, especially when compared to novel plasma and urinary biomarkers. However, the findings regarding its clinical use published so far provide insufficient evidence to recommend the generalized application of the test in daily clinical routine. Dosage, timing, and clinical outcomes of the FST proposed thus far have been significantly different, which further accentuates the need for standardization in the application of the test in order to facilitate the comparison of results between series. This review will summarize published research regarding the usefulness of the FST in different settings, providing the reader some insights about the possible implications of FST in clinical decision-making in patients with kidney disease and the challenges that research will have to address in the near future before widely applying the FST.

Indexed as

BiomarkersAcute Kidney InjuryClinical Decision-MakingDisease ManagementFurosemideHumansKidney Function TestsKidney TransplantationPrognosisSodium Potassium Chloride Symporter InhibitorsStress, PhysiologicalBiomarkersFurosemideSodium Potassium Chloride Symporter Inhibitorsacute kidney injuryfunctional assessmentfurosemide stress testrenal biomarkers

Identifiers

PMID32349337
PMCPMC7247682

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.