Evidence map›Paper›PMID 32349318›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Enrica Marchionni, Maria Grazia Porpora, Francesca Megiorni, Ilaria Piacenti, Agnese Giovannetti, Cinzia Marchese, Pierluigi Benedetti Panici, Antonio Pizzuti

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Enrica MarchionniDepartment of Experimental Medicine, Sapienza University of Rome, Policlinico Umberto I Hospital, 00161 Rome, Italy.
Maria Grazia PorporaDepartment of Maternal and Child Health and Urology, Sapienza University of Rome, Policlinico Umberto I Hospital, 00161 Rome, Italy.ORCID 0000-0001-5556-3933
Francesca MegiorniDepartment of Experimental Medicine, Sapienza University of Rome, Policlinico Umberto I Hospital, 00161 Rome, Italy.
Ilaria PiacentiDepartment of Maternal and Child Health and Urology, Sapienza University of Rome, Policlinico Umberto I Hospital, 00161 Rome, Italy.
Agnese GiovannettiLaboratory of Clinical Genomics, Fondazione IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy.ORCID 0000-0001-5207-7243
Cinzia MarcheseDepartment of Experimental Medicine, Sapienza University of Rome, Policlinico Umberto I Hospital, 00161 Rome, Italy.ORCID 0000-0002-9280-8917
Pierluigi Benedetti PaniciDepartment of Maternal and Child Health and Urology, Sapienza University of Rome, Policlinico Umberto I Hospital, 00161 Rome, Italy.
Antonio PizzutiDepartment of Experimental Medicine, Sapienza University of Rome, Policlinico Umberto I Hospital, 00161 Rome, Italy.
Policlinico Umberto I · ITCasa Sollievo della Sofferenza · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndometriosis is a widespread multifactorial disease in which environmental, genetic, and epigenetic factors contribute to the phenotype. Single Nucleotide Polymorphisms (SNPs) in genes implicated in pivotal molecular mechanisms have been investigated as susceptible risk factors in distinct populations. Among these, Toll-like receptor 4 (TLR4) represents a good candidate due to its role in the immune/inflammatory response and endometriosis pathogenesis.

methodsThe

resultsFisher's exact test comparing C and T allele frequencies showed a difference in the frequency of T alleles between patients and controls (OR = 1.96, 95% confidence interval 0.91-4.23;

conclusionsOur results show that the

Indexed as

endometriosisT399I polymorphismTLR4

Identifiers

PMID32349318
PMCPMC7277393
OpenAlexW3019446938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.