Evidence map›Paper›PMID 32349297›Full record

ReviewInternational journal of molecular sciences2020

Photoacoustic Imaging Probes Based on Tetrapyrroles and Related Compounds.

Jean Michel Merkes, Leiming Zhu, Srishti Ballabh Bahukhandi, Magnus Rueping, Fabian Kiessling, Srinivas Banala

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. The Physical Chemistry and Chemical Physics (PCCP) Section of theInternational journal of molecular sciences · 2021
    Article
  6. Article
  7. Advances in the Chemistry of Porphyrins and Related Macrocycles.International journal of molecular sciences · 2021
    Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jean Michel MerkesInstitute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074 Aachen, Germany.
Leiming ZhuInstitute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074 Aachen, Germany.
Srishti Ballabh BahukhandiInstitute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074 Aachen, Germany.
Magnus RuepingInstitute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074 Aachen, Germany.ORCID 0000-0003-4580-5227
Fabian KiesslingInstitute for Experimental Molecular Imaging, Forckenbeckstrasse 55, RWTH Aachen, University Clinic, 52074 Aachen, Germany.ORCID 0000-0002-7341-0399
Srinivas BanalaInstitute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074 Aachen, Germany.
RWTH Aachen University · DEKing Abdullah University of Science and Technology · SA

Funding

Deutsche Forschungsgemeinschaft (DFG) Research Training Group 2375; grant: 331065168Excellence Initiative of the German federal and state governments I3TM Seed Fund_SF_16-6-03
6 · The paper itself

Abstract

Photoacoustic imaging (PAI) is a rapidly evolving field in molecular imaging that enables imaging in the depths of ultrasound and with the sensitivity of optical modalities. PAI bases on the photoexcitation of a chromophore, which converts the absorbed light into thermal energy, causing an acoustic pressure wave that can be captured with ultrasound transducers, in generating an image. For in vivo imaging, chromophores strongly absorbing in the near-infrared range (NIR; > 680 nm) are required. As tetrapyrroles have a long history in biomedical applications, novel tetrapyrroles and inspired mimics have been pursued as potentially suitable contrast agents for PAI. The goal of this review is to summarize the current state of the art in PAI applications using tetrapyrroles and related macrocycles inspired by it, highlighting those compounds exhibiting strong NIR-absorption. Furthermore, we discuss the current developments of other absorbers for in vivo photoacoustic (PA) applications.

Indexed as

Photoacoustic TechniquesTetrapyrrolesContrast MediaDiagnostic ImagingIndolesIsoindolesMolecular ProbesMolecular StructurePorphyrinsContrast MediaIndolesIsoindolesMolecular ProbesphthalocyaninePorphyrinsTetrapyrrolesactivatable probesazacalixphyrincore-modified porphyrinsnear-infrared (NIR) dyesNIR-II dyesphthalocyaninesporphyrins

Identifiers

PMID32349297
PMCPMC7247687
OpenAlexW3019248630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.