Evidence map›Paper›PMID 32349263›Full record

ReviewInternational journal of molecular sciences2020

Recent Trends of microRNA Significance in Pediatric Population Glioblastoma and Current Knowledge of Micro RNA Function in Glioblastoma Multiforme.

Marek Mazurek, Cezary Grochowski, Jakub Litak, Ida Osuchowska, Ryszard Maciejewski, Piotr Kamieniak

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

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  16. mRNA and miRNA Expression Analyses of theInternational journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marek MazurekDepartment of Neurosurgery and Pediatric Neurosurgery, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland.
Cezary GrochowskiDepartment of Anatomy, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland.ORCID 0000-0002-2938-885X
Jakub LitakDepartment of Clinical Immunology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland.ORCID 0000-0001-7954-9263
Ida OsuchowskaDepartment of Anatomy, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland.
Ryszard MaciejewskiDepartment of Anatomy, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland.
Piotr KamieniakDepartment of Neurosurgery and Pediatric Neurosurgery, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland.
Medical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central nervous system tumors are a significant problem for modern medicine because of their location. The explanation of the importance of microRNA (miRNA) in the development of cancerous changes plays an important role in this respect. The first papers describing the presence of miRNA were published in the 1990s. The role of miRNA has been pointed out in many medical conditions such as kidney disease, diabetes, neurodegenerative disorder, arthritis and cancer. There are several miRNAs responsible for invasiveness, apoptosis, resistance to treatment, angiogenesis, proliferation and immunology, and many others. The research conducted in recent years analyzing this group of tumors has shown the important role of miRNA in the course of gliomagenesis. These particles seem to participate in many stages of the development of cancer processes, such as proliferation, angiogenesis, regulation of apoptosis or cell resistance to cytostatics.

Indexed as

Gene Expression Regulation, NeoplasticAge FactorsApoptosisBrain NeoplasmsCell Transformation, NeoplasticComputational BiologyGene Expression ProfilingGenetics, PopulationGlioblastomaHumansMicroRNAsMolecular Sequence AnnotationNeoplasm GradingNeovascularization, PathologicPediatricsPopulation SurveillanceMicroRNAschildrenglioblastoma multiformegliomahigh grade gliomamiRNApediatric populationRNA

Identifiers

PMID32349263
PMCPMC7246719
OpenAlexW3019442813

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.