ReviewLife (Basel, Switzerland)2020
Factoring Origin of Life Hypotheses into the Search for Life in the Solar System and Beyond.
Review in Life (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- RNA and proteins joined up at the Origins of Life: Persistence is the point.bioRxiv : the preprint server for biology · 2026Article
- Redox chemistry of early Earth and the origin of life.Communications chemistry · 2026Review
- Do-Nothing Prebiotic Chemistry: Chemical Kinetics as a Window into Prebiotic Plausibility.Accounts of chemical research · 2025Article
- Marine Science Can Contribute to the Search for Extra-Terrestrial Life.Life (Basel, Switzerland) · 2024Review
- Could Life Have Started on Mars? Planetary Conditions That Assemble and Destroy Protocells.Life (Basel, Switzerland) · 2024Article
- Configurations of Proto-Cell Aggregates with Anisotropy: Gravity Promotes Complexity in Theoretical Biology.Entropy (Basel, Switzerland) · 2022Article
- The Origin of Life: What Is the Question?Astrobiology · 2022Article
- Membrane Structure Obtained in an Experimental Evolution Process.Life (Basel, Switzerland) · 2022Article
- Was There Land on the Early Earth?Life (Basel, Switzerland) · 2021Review
- Formation of Thiophene under Simulated Volcanic Hydrothermal Conditions on Earth-Implications for Early Life on Extraterrestrial Planets?Life (Basel, Switzerland) · 2021Article
- Origin of Life: The Point of No Return.Life (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two widely-cited alternative hypotheses propose geological localities and biochemical mechanisms for life's origins. The first states that chemical energy available in submarine hydrothermal vents supported the formation of organic compounds and initiated primitive metabolic pathways which became incorporated in the earliest cells; the second proposes that protocells self-assembled from exogenous and geothermally-delivered monomers in freshwater hot springs. These alternative hypotheses are relevant to the fossil record of early life on Earth, and can be factored into the search for life elsewhere in the Solar System. This review summarizes the evidence supporting and challenging these hypotheses, and considers their implications for the search for life on various habitable worlds. It will discuss the relative probability that life could have emerged in environments on early Mars, on the icy moons of Jupiter and Saturn, and also the degree to which prebiotic chemistry could have advanced on Titan. These environments will be compared to ancient and modern terrestrial analogs to assess their habitability and biopreservation potential. Origins of life approaches can guide the biosignature detection strategies of the next generation of planetary science missions, which could in turn advance one or both of the leading alternative abiogenesis hypotheses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.