Evidence map›Paper›PMID 32349176›Full record

ReviewTransplant international : official journal of the European Society for Organ Transplantation2020

Global Kidney Exchange: opportunity or exploitation? An ELPAT/ESOT appraisal.

Frederike Ambagtsheer, Bernadette Haase-Kromwijk, Frank J M F Dor, Greg Moorlock, Franco Citterio, Thierry Berney, Emma K Massey

Abstract readReview
In one paragraph

Review in Transplant international : official journal of the European Society for Organ Transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Global kidney chains.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  6. Popular repugnance contrasts with legal bans on controversial markets.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Frederike AmbagtsheerDepartment of Internal Medicine, Nephrology & Transplantation, Erasmus MC, Rotterdam, The Netherlands.ORCID 0000-0002-3232-6449
Bernadette Haase-KromwijkDutch Transplant Foundation, Leiden, The Netherlands.
Frank J M F DorImperial College Renal and Transplant Centre, Hammersmith Hospital, London, UK.
Greg MoorlockWarwick Medical School, University of Warwick, Coventry, UK.
Franco CitterioRenal Transplantation Unit, Fondazione Policlinico Universitario, A. Gemelli, Rome, Italy.
Thierry BerneyDivision of Transplantation, University of Geneva Hospitals, Geneva, Switzerland.ORCID 0000-0002-4230-9378
Emma K MasseyDepartment of Internal Medicine, Nephrology & Transplantation, Erasmus MC, Rotterdam, The Netherlands.ORCID 0000-0002-9017-1924

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper addresses ethical, legal, and psychosocial aspects of Global Kidney Exchange (GKE). Concerns have been raised that GKE violates the nonpayment principle, exploits donors in low- and middle-income countries, and detracts from the aim of self-sufficiency. We review the arguments for and against GKE. We argue that while some concerns about GKE are justified based on the available evidence, others are speculative and do not apply exclusively to GKE but to living donation more generally. We posit that concerns can be mitigated by implementing safeguards, by developing minimum quality criteria and by establishing an international committee that independently monitors and evaluates GKE's procedures and outcomes. Several questions remain however that warrant further clarification. What are the experiences and views of recipients and donors participating in GKE? Who manages the escrow funds that have been put in place for donor and recipients? What procedures and safeguards have been put in place to prevent corruption of these funds? What are the inclusion criteria for participating GKE centers? GKE provides opportunity to promote access to donation and transplantation but can only be conducted with the appropriate safeguards. Patients' and donors' voices are missing in this debate.

Indexed as

Kidney TransplantationTissue and Organ ProcurementHumansKidneyLiving Donorschronic kidney diseasekidney transplantationliving donationmedical ethicsorgan trafficking

Identifiers

PMID32349176
PMCPMC7540591

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.