Evidence map›Paper›PMID 32348763›Full record

ArticleCell reports2020

CD4

Jinsheng Wen, Ying-Ting Wang, Kristen M Valentine, Rúbens Prince Dos Santos Alves, Zhigang Xu, Jose Angel Regla-Nava, Annie Elong Ngono, Matthew P Young, Luís C S Ferreira, Sujan Shresta

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Human coronavirus OC43-elicited CD4Nature communications · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 3 countries.

Jinsheng WenDivision of Inflammation Biology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA; Immunology Innovation Team, Ningbo University School of Medicine, Ningbo, Zhejiang 315211, China. Electronic address: wenjinsheng@nbu.edu.cn.
Ying-Ting WangDivision of Inflammation Biology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Kristen M ValentineDivision of Inflammation Biology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Rúbens Prince Dos Santos AlvesDivision of Inflammation Biology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA; Vaccine Development Laboratory, Institute of Biomedical Sciences, University of São Paulo, São Paulo 14040-901, Brazil.
Zhigang XuDivision of Inflammation Biology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Jose Angel Regla-NavaDivision of Inflammation Biology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Annie Elong NgonoDivision of Inflammation Biology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Matthew P YoungDivision of Inflammation Biology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Luís C S FerreiraVaccine Development Laboratory, Institute of Biomedical Sciences, University of São Paulo, São Paulo 14040-901, Brazil.
Sujan ShrestaDivision of Inflammation Biology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA. Electronic address: sujan@lji.org.
La Jolla Institute for Immunology · USUniversidade de São Paulo · BR

Funding

U of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, ZHENG, BINHAI · 2003 to 2022
$9.0M
Training in Immunological MechanismsT32AI125179 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2016 to 2025
$3.1M
Molecular basis of Zika-induced microcephalyR01NS106387 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G · 2018 to 2021
$2.2M
IRF-3/5/7-Independent Antiviral ImmunityR01AI116813 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI SHRESTA, SUJAN · 2016 to 2019
$1.9M
Vaginal Adaptive Immunity Against Zika VirusR21AI140063 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI SHRESTA, SUJAN · 2018 to 2019
$495k
NIAID NIH HHS R01 AI116813NIAID NIH HHS R21 AI140063NIAID NIH HHS T32 AI125179NINDS NIH HHS P30 NS047101NINDS NIH HHS R01 NS106387
6 · The paper itself

Abstract

The underlying mechanisms by which prior immunity to dengue virus (DENV) affords cross-protection against the related flavivirus Zika virus (ZIKV) are poorly understood. Here, we examine the ability of DENV/ZIKV-cross-reactive CD4

Indexed as

AnimalsCD4-Positive T-LymphocytesCross ReactionsDengueDengue VirusDisease Models, AnimalHumansMiceZika VirusZika Virus InfectionCD4+cross-protectioncross-reactivedengue virusIFNγmousepeptideT cellTh1TNFZika virus

Identifiers

PMID32348763
PMCPMC7261136
OpenAlexW3018330485

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.