Evidence map›Paper›PMID 32348669›Full record

ArticleJournal of the American Chemical Society2020

Mechanism of Rate Acceleration of Radical C-C Bond Formation Reaction by a Radical SAM GTP 3',8-Cyclase.

Haoran Pang, Edward A Lilla, Pan Zhang, Du Zhang, Thomas P Shields, Lincoln G Scott, Weitao Yang, Kenichi Yokoyama

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. RadicalJournal of the American Chemical Society · 2026
    Article
  2. Mechanism of controlled radical initiation in radical SAM GTP 3',8-cyclase.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Molybdenum Cofactor Deficiency in Humans.Molecules (Basel, Switzerland) · 2022
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Haoran PangDepartment of Biochemistry, Duke University School of Medicine, Durham, North Carolina 27710, United States.
Edward A LillaDepartment of Biochemistry, Duke University School of Medicine, Durham, North Carolina 27710, United States.
Pan ZhangDepartment of Chemistry, Duke University, Durham, North Carolina 27710, United States.
Du ZhangDepartment of Chemistry, Duke University, Durham, North Carolina 27710, United States.
Thomas P ShieldsCassia, LLC, 3030 Bunker Hill Street, Suite 214, San Diego, California 92109, United States.
Lincoln G ScottCassia, LLC, 3030 Bunker Hill Street, Suite 214, San Diego, California 92109, United States.
Weitao YangDepartment of Chemistry, Duke University, Durham, North Carolina 27710, United States.ORCID 0000-0001-5576-2828
Kenichi YokoyamaDepartment of Biochemistry, Duke University School of Medicine, Durham, North Carolina 27710, United States.ORCID 0000-0001-5625-469X
Duke University · USCassia (United States) · US

Funding

COMPUTER SIMULATIONS OF ENZYMES AND DNAR01GM061870 · NIGMS · DUKE UNIVERSITY · PI YANG, WEITAO · 2000 to 2022
$5.5M
Mechanism of cofactor biosynthesis required for chronic bacterial infectionR01GM112838 · NIGMS · DUKE UNIVERSITY · PI YOKOYAMA, KENICHI · 2015 to 2023
$2.8M
NIGMS NIH HHS R01 GM061870NIGMS NIH HHS R01 GM112838
6 · The paper itself

Abstract

While the number of characterized radical

Indexed as

Density Functional TheoryEscherichia coli ProteinsFree RadicalsIsomerasesMolecular ConformationS-AdenosylmethionineEscherichia coli ProteinsFree RadicalsIsomerasesMoaA protein, E coliS-Adenosylmethionine

Identifiers

PMID32348669
PMCPMC7256450
OpenAlexW3019665538

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.