Evidence map›Paper›PMID 32348598›Full record

ReviewAlimentary pharmacology & therapeutics2020

Review article: prevention, diagnosis and management of COVID-19 in the IBD patient.

Aysha H Al-Ani, Ralley E Prentice, Clarissa A Rentsch, Doug Johnson, Zaid Ardalan, Neel Heerasing, Mayur Garg, Sian Campbell, Joe Sasadeusz, Finlay A Macrae and 3 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Alimentary pharmacology & therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 3 pooled it
2.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 3 syntheses or guidelines pooled it, 107 citations in OpenAlex.

  1. Pooled it
  2. Remote care through telehealth for people with inflammatory bowel disease.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Guideline
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Diarrhea and Coronavirus Disease 2019 Infection.Gastroenterology clinics of North America · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. COVID-19 induces gastrointestinal symptoms and affects patients' prognosis.The Journal of international medical research · 2022
    Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Letter: association between COVID-19 and inflammatory bowel disease.Alimentary pharmacology & therapeutics · 2022
    Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Aysha H Al-AniDepartment of Gastroenterology, The Royal Melbourne Hospital, Melbourne, Vic., Australia.
Ralley E PrenticeDepartment of Gastroenterology, The Royal Melbourne Hospital, Melbourne, Vic., Australia.
Clarissa A RentschDepartment of Gastroenterology, The Royal Melbourne Hospital, Melbourne, Vic., Australia.
Doug JohnsonVictorian Infectious Diseases Unit, The Royal Melbourne Hospital, Melbourne, Vic., Australia.
Zaid ArdalanDepartment of Gastroenterology, The Royal Melbourne Hospital, Melbourne, Vic., Australia.ORCID 0000-0001-6952-0985
Neel HeerasingDepartment of Gastroenterology, The Royal Melbourne Hospital, Melbourne, Vic., Australia.ORCID 0000-0003-0579-2062
Mayur GargDepartment of Gastroenterology, The Royal Melbourne Hospital, Melbourne, Vic., Australia.ORCID 0000-0002-9149-3589
Sian CampbellVictorian Infectious Diseases Unit, The Royal Melbourne Hospital, Melbourne, Vic., Australia.
Joe SasadeuszVictorian Infectious Diseases Unit, The Royal Melbourne Hospital, Melbourne, Vic., Australia.
Finlay A MacraeDepartment of Gastroenterology, The Royal Melbourne Hospital, Melbourne, Vic., Australia.
Siew C NgDepartment of Medicine and Therapeutics, Institute of Digestive Disease, State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.ORCID 0000-0002-6850-4454
David T RubinInflammatory Bowel Disease Center, University of Chicago Medicine, Chicago, IL, USA.ORCID 0000-0001-5647-1723
Britt ChristensenDepartment of Gastroenterology, The Royal Melbourne Hospital, Melbourne, Vic., Australia.ORCID 0000-0002-8746-4275
The Royal Melbourne Hospital · AUChinese University of Hong Kong · HKUniversity of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe current COVID-19 pandemic, caused by SARS-CoV-2, has emerged as a public health emergency. All nations are seriously challenged as the virus spreads rapidly across the globe with no regard for borders. The primary management of IBD involves treating uncontrolled inflammation with most patients requiring immune-based therapies. However, these therapies may weaken the immune system and potentially place IBD patients at increased risk of infections and infectious complications including those from COVID-19.

aimTo summarise the scale of the COVID-19 pandemic, review unique concerns regarding IBD management and infection risk during the pandemic and assess COVID-19 management options and drug interactions in the IBD population.

methodsA literature review on IBD, SARS-CoV-2 and COVID-19 was undertaken and relevant literature was summarised and critically examined.

resultsIBD patients do not appear to be more susceptible to SARS-CoV-2 infection and there is no evidence of an association between IBD therapies and increased risk of COVID-19. IBD medication adherence should be encouraged to prevent disease flare but where possible high-dose systemic corticosteroids should be avoided. Patients should exercise social distancing, optimise co-morbidities and be up to date with influenza and pneumococcal vaccines. If a patient develops COVID-19, immune suppressing medications should be withheld until infection resolution and if trial medications for COVID-19 are being considered, potential drug interactions should be checked.

conclusionsIBD patient management presents a challenge in the current COVID-19 pandemic. The primary focus should remain on keeping bowel inflammation controlled and encouraging medication adherence.

Indexed as

BetacoronavirusComorbidityCoronavirus InfectionsCOVID-19HumansInflammationInflammatory Bowel DiseasesPandemicsPneumonia, ViralSARS-CoV-2

Identifiers

PMID32348598
PMCPMC7267115
OpenAlexW3017731458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.