ArticleJournal of medical virology2020
Metformin and COVID-19: A novel deal of an old drug.
Article in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The Efficacy and Potential Mechanisms of Metformin in the Treatment of COVID-19 in the Diabetics: A Systematic Review.Frontiers in endocrinology · 2021Pooled it
- Obesity aggravates COVID-19: A systematic review and meta-analysis.Journal of medical virology · 2021Pooled it
- The Effect of Metformin Consumption on Mortality in Hospitalized COVID-19 patients: a systematic review and meta-analysis.Diabetes & metabolic syndromePooled it
- NLRP3 inflammasomes pathway: a key target for Metformin.Inflammopharmacology · 2025Review
- Is Metformin Use Associated with a More Favorable COVID-19 Course in People with Diabetes?Journal of clinical medicine · 2024Article
- Systematic Investigation of Dose-Dependent Protein Thermal Stability Changes to Uncover the Mechanisms of the Pleiotropic Effects of Metformin.ACS pharmacology & translational science · 2024Article
- Clinical and Laboratory Data Up on Hospital Admission are Predictors of New-Onset Atrial Fibrillation in Patients Hospitalized Due to COVID-19 Pneumonia.Arquivos brasileiros de cardiologia · 2024Observational
- Investigating the impact of metformin on severity of COVID-19 in patients with Type 2 diabetes mellitus: Focusing on laboratory findings.Endocrinology, diabetes & metabolism · 2023Article
- Metformin as a promising target for DPP4 expression: computational modeling and experimental validation.Medical oncology (Northwood, London, England) · 2023Article
- Therapeutic role of mTOR inhibitors in control of SARS-CoV-2 viral replication.Molecular biology reports · 2023Review
- Current Strategies in Treating Cytokine Release Syndrome Triggered by Coronavirus SARS-CoV-2.ImmunoTargets and therapy · 2022Review
- Impact of theInfection and drug resistance · 2022Article
- The roles of dipeptidyl peptidase-4 inhibitors in prognosis of COVID-19 infection in patients with type 2 diabetes mellitus.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022Article
- A review on protective roles and potential mechanisms of metformin in diabetic patients diagnosed with COVID-19.Metabolism open · 2021Article
- Drug-based therapeutic strategies for COVID-19-infected patients and their challenges.Future microbiology · 2021Review
- Metformin Use Is Associated with Decreased Mortality in COVID-19 Patients with Diabetes: Evidence from Retrospective Studies and Biological Mechanism.Journal of clinical medicine · 2021Article
- Outcome and death risk of diabetes patients with Covid-19 receiving pre-hospital and in-hospital metformin therapies.Diabetology & metabolic syndrome · 2021Article
- Metformin use and risk of COVID-19 among patients with type II diabetes mellitus: an NHIS-COVID-19 database cohort study.Acta diabetologica · 2021Article
- Does higher body mass index increase COVID-19 severity? A systematic review and meta-analysis.Obesity medicine · 2021Article
- Commentary: Providing optimal care for cardiothoracic patients of the future requires expertise spanning barriers of time and specialization.The Journal of thoracic and cardiovascular surgery · 2021Article
Corrections and comments
- Commented on by
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.