Evidence map›Paper›PMID 32347813›Full record

ArticleJournal of medical Internet research2020

Development, Implementation, and Evaluation of a Personalized Machine Learning Algorithm for Clinical Decision Support: Case Study With Shingles Vaccination.

Ji Chen, Sara Chokshi, Roshini Hegde, Javier Gonzalez, Eduardo Iturrate, Yin Aphinyanaphongs, Devin Mann

Open access · goldAbstract read
In one paragraph

Article in Journal of medical Internet research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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  4. Applying Machine Learning Techniques to Implementation Science.Online journal of public health informatics · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ji ChenDepartment of Population Health, New York University School of Medicine, New York, NY, United States.ORCID 0000-0002-4856-0141
Sara ChokshiDepartment of Population Health, New York University School of Medicine, New York, NY, United States.ORCID 0000-0002-3952-6654
Roshini HegdeDepartment of Population Health, New York University School of Medicine, New York, NY, United States.ORCID 0000-0001-7740-1898
Javier GonzalezMedical Center Information Technology, New York University Langone Health, New York, NY, United States.ORCID 0000-0002-7562-6070
Eduardo IturrateClinical Informatics, New York University School of Medicine, New York, NY, United States.ORCID 0000-0001-6434-2518
Yin AphinyanaphongsDepartment of Population Health, New York University School of Medicine, New York, NY, United States.ORCID 0000-0001-8605-5392
Devin MannDepartment of Population Health, New York University School of Medicine, New York, NY, United States.ORCID 0000-0002-2099-0852
New York University · USNYU Langone Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough clinical decision support (CDS) alerts are effective reminders of best practices, their effectiveness is blunted by clinicians who fail to respond to an overabundance of inappropriate alerts. An electronic health record (EHR)-integrated machine learning (ML) algorithm is a potentially powerful tool to increase the signal-to-noise ratio of CDS alerts and positively impact the clinician's interaction with these alerts in general.

objectiveThis study aimed to describe the development and implementation of an ML-based signal-to-noise optimization system (SmartCDS) to increase the signal of alerts by decreasing the volume of low-value herpes zoster (shingles) vaccination alerts.

methodsWe built and deployed SmartCDS, which builds personalized user activity profiles to suppress shingles vaccination alerts unlikely to yield a clinician's interaction. We extracted all records of shingles alerts from January 2017 to March 2019 from our EHR system, including 327,737 encounters, 780 providers, and 144,438 patients.

resultsDuring the 6 weeks of pilot deployment, the SmartCDS system suppressed an average of 43.67% (15,425/35,315) potential shingles alerts (appointments) and maintained stable counts of weekly shingles vaccination orders (326.3 with system active vs 331.3 in the control group; P=.38) and weekly user-alert interactions (1118.3 with system active vs 1166.3 in the control group; P=.20).

conclusionsAll key statistics remained stable while the system was turned on. Although the results are promising, the characteristics of the system can be subject to future data shifts, which require automated logging and monitoring. We demonstrated that an automated, ML-based method and data architecture to suppress alerts are feasible without detriment to overall order rates. This work is the first alert suppression ML-based model deployed in practice and serves as foundational work in encounter-level customization of alert display to maximize effectiveness.

Indexed as

AlgorithmsDecision Support Systems, ClinicalHerpes ZosterHumansMachine LearningPilot ProjectsPrecision MedicineVaccinationalert fatigueclinical decision supportimplementation sciencemachine learning

Identifiers

PMID32347813
PMCPMC7221637
OpenAlexW3006894494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.