Evidence map›Paper›PMID 32347794›Full record

ArticleeLife2020

Probabilistic, spinally-gated control of bladder pressure and autonomous micturition by Barrington's nucleus CRH neurons.

Hiroki Ito, Anna C Sales, Christopher H Fry, Anthony J Kanai, Marcus J Drake, Anthony E Pickering

Abstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Urogenital dysfunction in neurological diseases.Nature reviews. Neurology · 2026
    Review
  5. Article
  6. From bladder to brain: How you know when it's time to go.Current opinion in neurobiology · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Neural circuit control of innate behaviors.Science China. Life sciences · 2022
    Review
  17. Article
  18. Corticotropin-Releasing Hormone from the Pontine Micturition Center Plays an Inhibitory Role in Micturition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  19. Social isolation uncovers a circuit underlying context-dependent territory-covering micturition.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hiroki Ito *School of Physiology, Pharmacology and Neuroscience, Faculty of Life Sciences, University of Bristol, Bristol, United Kingdom.
Anna C Sales *School of Physiology, Pharmacology and Neuroscience, Faculty of Life Sciences, University of Bristol, Bristol, United Kingdom.ORCID 0000-0001-8585-3763
Christopher H FrySchool of Physiology, Pharmacology and Neuroscience, Faculty of Life Sciences, University of Bristol, Bristol, United Kingdom.
Anthony J KanaiDepartment of Medicine and Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, United States.
Marcus J DrakeSchool of Physiology, Pharmacology and Neuroscience, Faculty of Life Sciences, University of Bristol, Bristol, United Kingdom.
Anthony E PickeringSchool of Physiology, Pharmacology and Neuroscience, Faculty of Life Sciences, University of Bristol, Bristol, United Kingdom.ORCID 0000-0003-0345-0456

Funding

PDE5 Inhibition of Afferents and Interstitial Cells in Overactive Mouse BladdersR01DK098361 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRDER, LORI A, KANAI, ANTHONY JOHN · 2014 to 2024
$5.7M
NIDDK NIH HHS R01 DK098361NIH HHS R01 DK098361Wellcome 108899/Z/15
6 · The paper itself

Abstract

Micturition requires precise control of bladder and urethral sphincter via parasympathetic, sympathetic and somatic motoneurons. This involves a spino-bulbospinal control circuit incorporating Barrington's nucleus in the pons (Barr). Ponto-spinal glutamatergic neurons that express corticotrophin-releasing hormone (CRH) form one of the largest Barr cell populations. Barr

Indexed as

AnimalsBarrington's NucleusCorticotropin-Releasing HormoneMiceNeural PathwaysNeuronsPonsSpinal CordUrinary BladderUrinationCorticotropin-Releasing Hormonebarrington's nucleusbladderbrainstemmicturitionmouseneuroscience

Identifiers

PMID32347794
PMCPMC7217699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.