Evidence map›Paper›PMID 32347766›Full record

ArticleEnvironmental health perspectives2020

Design and Rationale of the HAPIN Study: A Multicountry Randomized Controlled Trial to Assess the Effect of Liquefied Petroleum Gas Stove and Continuous Fuel Distribution.

Thomas Clasen, William Checkley, Jennifer L Peel, Kalpana Balakrishnan, John P McCracken, Ghislaine Rosa, Lisa M Thompson, Dana Boyd Barr, Maggie L Clark, Michael A Johnson and 11 more

Registry-linked trialOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental health perspectives, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02944682 (Household Air Pollution and Health), which is not on this map. Cited by 83 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02944682 nacompletednot on this map

Household Air Pollution and Health: A Multi-country LPG Intervention Trial

TypeinterventionalSponsorEmory UniversityRan2017 to 2025Enrolled3,640ConditionsInfant, Low Birth WeightArmsLiquefied petroleum gas (LPG) cookstove
3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 1 synthesis or guideline pooled it, 119 citations in OpenAlex.

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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 12 institutions in 5 countries.

Thomas ClasenDepartment of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
William CheckleyDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Jennifer L PeelDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado, USA.
Kalpana BalakrishnanDepartment of Environmental Health Engineering, ICMR Center for Advanced Research on Air Quality, Climate and Health, Sri Ramachandra Institute for Higher Education and Research (Deemed University), Chennai, Tamil Nadu, India.
John P McCrackenCenter for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
Ghislaine RosaDepartment of Disease Control, Faculty of Infections and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Lisa M ThompsonNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia, USA.
Dana Boyd BarrDepartment of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Maggie L ClarkDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado, USA.
Michael A JohnsonBerkeley Air Monitoring Group, Berkeley, California, USA.
Lance A WallerDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Lindsay M JaacksDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Kyle SteenlandDepartment of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
J Jaime MirandaCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
Howard H ChangDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Dong-Yun KimOffice of Biostatistics Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Eric D McCollumEudowood Division of Respiratory Sciences, Department of Pediatrics, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Victor G Davila-RomanCardiovascular Imaging and Clinical Research Core Laboratory, Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri, USA.
Aris PapageorghiouNuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.
Joshua P RosenthalDivision of Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA.
HAPIN Investigators
Emory University · USColorado State University · USJohns Hopkins University · USNational Institutes of Health · USBerkeley Air Monitoring Group (United States) · USHarvard Global Health Institute · USLondon School of Hygiene & Tropical Medicine · GBSri Ramachandra Institute of Higher Education and Research · INUniversidad del Valle de Guatemala · GTUniversidad Peruana Cayetano Heredia · PEUniversity of Oxford · GBWashington University in St. Louis · US

Funding

Household Air Pollution and Health: A Multi-Country LPG Intervention TrialUM1HL134590 · NHLBI · EMORY UNIVERSITY · PI CHECKLEY, WILLIAM, CLASEN, THOMAS F · 2016 to 2021
$31.1M
Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI William Michael Caudle · 2013 to 2026
$22.6M
NCIPC CDC HHS R01 CE002981NHLBI NIH HHS UM1 HL134590NIEHS NIH HHS P30 ES019776
6 · The paper itself

Abstract

backgroundGlobally, nearly 3 billion people rely on solid fuels for cooking and heating, the vast majority residing in low- and middle-income countries (LMICs). The resulting household air pollution (HAP) is a leading environmental risk factor, accounting for an estimated 1.6 million premature deaths annually. Previous interventions of cleaner stoves have often failed to reduce exposure to levels that produce meaningful health improvements. There have been no multicountry field trials with liquefied petroleum gas (LPG) stoves, likely the cleanest scalable intervention.

objectiveThis paper describes the design and methods of an ongoing randomized controlled trial (RCT) of LPG stove and fuel distribution in 3,200 households in 4 LMICs (India, Guatemala, Peru, and Rwanda).

methodsWe are enrolling 800 pregnant women at each of the 4 international research centers from households using biomass fuels. We are randomly assigning households to receive LPG stoves, an 18-month supply of free LPG, and behavioral reinforcements to the control arm. The mother is being followed along with her child until the child is 1 year old. Older adult women (40 to

conclusionsThis study will provide evidence to inform national and global policies on scaling up LPG stove use among vulnerable populations. https://doi.org/10.1289/EHP6407.

Indexed as

Randomized Controlled Trials as TopicAdultAgedAir PollutantsAir Pollution, IndoorCookingFemaleGuatemalaHumansIndiaInfantInfant, NewbornMiddle AgedNatural GasParticulate MatterPeruAir PollutantsNatural GasParticulate Matter

Identifiers

PMID32347766
PMCPMC7228119
OpenAlexW3018992794

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.