Evidence map›Paper›PMID 32347333›Full record

ReviewDer Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft2020

[Eye changes in space : New insights into clinical aspects, pathogenesis and prevention].

A Händel, C Stern, J Jordan, T Dietlein, P Enders, C Cursiefen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. [Space-eye-disease: outer space, eye and glaucoma].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A HändelZentrum für Augenheilkunde, Universitätsklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland. alexander.haendel@uk-koeln.de.
C SternInstitut für Luft- und Raumfahrtmedizin, Deutsches Zentrum für Luft- und Raumfahrt (DLR), Köln, Deutschland.
J JordanInstitut für Luft- und Raumfahrtmedizin, Deutsches Zentrum für Luft- und Raumfahrt (DLR), Köln, Deutschland.
T DietleinZentrum für Augenheilkunde, Universitätsklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
P EndersZentrum für Augenheilkunde, Universitätsklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
C CursiefenZentrum für Augenheilkunde, Universitätsklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMore than ever research into changes in the eye caused by long-term space flight is becoming the focus of the international and national space agencies National Aeronautics and Space Administration (NASA), European Space Agency (ESA) and German Aerospace Center (DLR). In addition to space radiation-induced cataract formation considerable eye changes, summarized under space flight-associated neuro-ocular syndrome (SANS), can occur.

objectiveThis article gives an overview of the current state of research and future directions in the field of research concerned with ocular alterations in SANS and presents the relevance for terrestrial ophthalmological research. MATERIAL AND

methodsAn analysis of existing publications on SANS in PubMed and reports on the risk of SANS published by the NASA of the USA was carried out.

resultsThe reasons for the development of the eye changes in space have not been clarified. Factors such as the increase in intracranial pressure, fluid shifts, hypercapnia and genetic factors are the subject of intensive research efforts. A terrestrial model for the induction of papilledema could be established (bed rest studies with -6° head-down tilt as a space analogue). Countermeasures for the development of eye changes, such as intermittent artificial gravity, are the subject of current research studies.

conclusionResearch into SANS as part of bed rest studies will provide further important insights in the future for space research and also for terrestrial research. Clinical research projects can be derived from space research.

Indexed as

EyeSpace FlightHead-Down TiltHumansIntracranial PressurePapilledemaBed rest studiesIntracranial pressureIntraocular pressurePapilledemaSpace flight-associated neuro-ocular syndrome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.