Evidence map›Paper›PMID 32347157›Full record

ArticleJournal of neurophysiology2020

Neurotransmitter networks in mouse prefrontal cortex are reconfigured by isoflurane anesthesia.

Xiaoying Zhang, Aaron G Baer, Joshua M Price, Piet C Jones, Benjamin J Garcia, Jonathon Romero, Ashley M Cliff, Weidong Mi, James B Brown, Daniel A Jacobson and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Xiaoying ZhangDepartment of Anesthesiology, University of Tennessee Medical Center, Knoxville, Tennessee.
Aaron G BaerDepartment of Anesthesiology, University of Tennessee Medical Center, Knoxville, Tennessee.
Joshua M PriceOffice of Information Technology, University of Tennessee, Knoxville, Tennessee.ORCID 0000-0003-3246-278x
Piet C JonesOak Ridge National Laboratory, Oak Ridge, Tennessee.
Benjamin J GarciaOak Ridge National Laboratory, Oak Ridge, Tennessee.ORCID 0000-0001-5524-6946
Jonathon RomeroOak Ridge National Laboratory, Oak Ridge, Tennessee.ORCID 0000-0001-5249-1946
Ashley M CliffOak Ridge National Laboratory, Oak Ridge, Tennessee.
Weidong MiAnesthesia and Operation Center, Chinese PLA General Hospital, Beijing, China.
James B BrownMolecular Ecosystems Biology Department, Lawrence Berkeley National Laboratory, Berkeley, California.
Daniel A JacobsonOak Ridge National Laboratory, Oak Ridge, Tennessee.ORCID 0000-0002-9822-8251
Ralph LydicDepartment of Anesthesiology, University of Tennessee Medical Center, Knoxville, Tennessee.ORCID 0000-0002-2686-251X
Helen A BaghdoyanDepartment of Anesthesiology, University of Tennessee Medical Center, Knoxville, Tennessee.ORCID 0000-0003-0627-2448
University of Tennessee at Knoxville · USOak Ridge National Laboratory · USChinese PLA General Hospital · CNLawrence Berkeley National Laboratory · USUniversity Radiology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study quantified eight small-molecule neurotransmitters collected simultaneously from prefrontal cortex of C57BL/6J mice (

Indexed as

AnesthesiaMachine LearningNerve NetPrefrontal CortexAcetylcholineAdenosineAnesthetics, InhalationAnimalsIsofluraneMaleMiceMice, Inbred C57BLMicrodialysisNorepinephrineUnconsciousnessWakefulnessAcetylcholineAdenosineAnesthetics, InhalationIsofluraneNorepinephrineacetylcholineadenosineliquid chromatography-dual mass spectrometryloss of consciousnessmachine learning

Identifiers

PMID32347157
PMCPMC7311717
OpenAlexW3017727512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.