Evidence map›Paper›PMID 32347153›Full record

ReviewGut microbes2020

Exposure to air pollutants and the gut microbiota: a potential link between exposure, obesity, and type 2 diabetes.

Maximillian J Bailey, Noopur N Naik, Laura E Wild, William B Patterson, Tanya L Alderete

Open access · goldAbstract readReview
In one paragraph

Review in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 128 citations in OpenAlex.

  1. The effect of ambient ozone exposure on three types of diabetes: a meta-analysis.Environmental health : a global access science source · 2023
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Prenatal Nitrogen Oxide (NOEnvironmental science & technology · 2025
    Article
  12. Review
  13. Review
  14. Effects of Particulate Matter on Obstructive Sleep Apnea and Obesity.Journal of rhinology : official journal of the Korean Rhinologic Society · 2025
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Maximillian J BaileyDepartment of Integrative Physiology, University of Colorado Boulder , Boulder, CO, USA.
Noopur N NaikDepartment of Integrative Physiology, University of Colorado Boulder , Boulder, CO, USA.
Laura E WildDepartment of Integrative Physiology, University of Colorado Boulder , Boulder, CO, USA.
William B PattersonDepartment of Integrative Physiology, University of Colorado Boulder , Boulder, CO, USA.ORCID 0000-0001-8355-0857
Tanya L AldereteDepartment of Integrative Physiology, University of Colorado Boulder , Boulder, CO, USA.ORCID 0000-0002-7751-9543
University of Colorado Boulder · US

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Wendy M Kohrt · 1995 to 2026
$32.6M
Near-Roadway and Ambient Air Pollution Exposure and the Gut Microbiome: Implications for Obesity and Insulin Resistance in AdolescenceR00ES027853 · NIEHS · UNIVERSITY OF COLORADO · PI ALDERETE, TANYA LYNN · 2018 to 2020
$721k
NIDDK NIH HHS P30 DK048520NIEHS NIH HHS R00 ES027853
6 · The paper itself

Abstract

Work has shown that increased exposure to air pollutants independently contributes to obesity and type 2 diabetes risk, yet the exact mechanisms underlying these associations have not been fully characterized. The current review summarizes recent findings regarding the impact of inhaled and ingested air pollutants on the gut microbiota. Animal and human studies provide evidence that air pollutants, such as particulate matter, nitrogen oxides, and ozone, have the potential to alter the gut microbiota. Further, studies suggest that such exposure-induced alterations to the gut microbiota may contribute to increased risk for obesity and type 2 diabetes through inflammatory pathways. Future work is needed to fully understand the complex interactions between air pollution, the gut microbiome, and human health. Additionally, advanced sequencing methods for gut microbiome research present unique opportunities to study the underlying pathways that link increased air pollution exposure with obesity and type 2 diabetes risk.

Indexed as

Gastrointestinal MicrobiomeAir PollutantsAir PollutionAnimalsBacteriaDiabetes Mellitus, Type 2Gastrointestinal TractHumansInflammationModels, AnimalObesityParticulate MatterRisk FactorsAir PollutantsParticulate MatterAir pollutiongut healthgut microbiotaobesitytype 2 diabetes

Identifiers

PMID32347153
PMCPMC7524284
OpenAlexW3018721694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.