Observational studyJournal of the American Heart Association2020
Patient and Institutional Characteristics Influence the Decision to Use Extracorporeal Cardiopulmonary Resuscitation for In-Hospital Cardiac Arrest.
Observational study in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Extracorporeal cardiopulmonary resuscitation in patients with traumatic cardiac arrest during the acute phase following injury: a comprehensive systematic review and meta-analysis.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025Pooled it
- Extracorporeal Cardiopulmonary Resuscitation for Refractory Out-of-Hospital Cardiac Arrest (EROCA): Results of a Randomized Feasibility Trial of Expedited Out-of-Hospital Transport.Annals of emergency medicine · 2021Trial
- Extracorporeal cardiopulmonary resuscitation for in-hospital cardiac arrest: a comparative cohort study from the first ECPR program in Brazil.Resuscitation plus · 2026Article
- Predictors of Bleeding Complications After Extracorporeal Cardiopulmonary Resuscitation: Insights From the SAVE-J II Study.JACC. Asia · 2026Article
- Extracorporeal Cardiopulmonary Resuscitation for In-Hospital Cardiac Arrest: A Single-Center Experience in Latin America.Arquivos brasileiros de cardiologia · 2026Article
- The effect of percutaneous coronary intervention after extracorporeal cardiopulmonary resuscitation on survival for out of hospital cardiac arrest: a causal inference analysis.Resuscitation plus · 2025Article
- Risk factors and outcome of extracorporeal cardiopulmonary resuscitation patients with out-of-hospital cardiac arrest and in-hospital cardiac arrest: a nationwide prospective and observational study of 939 hospitals in China.BMC emergency medicine · 2025Observational
- Early Albumin Administration in Veno-Arterial Extracorporeal Membrane Oxygenation.Artificial organs · 2025Observational
- Development of a health equity tool in resuscitation sciences and application to current research in extracorporeal cardiopulmonary resuscitation for cardiac arrest.Resuscitation · 2025Review
- External Validation of the RESCUE-IHCA Score as a Predictor for In-Hospital Cardiac Arrest Patients Receiving Extracorporeal Cardiopulmonary Resuscitation.The western journal of emergency medicine · 2024Observational
- Extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest: Lessons learned from recent clinical trials.Journal of the American College of Emergency Physicians open · 2024Review
- The state of emergency department extracorporeal cardiopulmonary resuscitation: Where are we now, and where are we going?Journal of the American College of Emergency Physicians open · 2024Review
- Extracorporeal membrane oxygenation for cardiac arrest: what, when, why, and how.Expert review of respiratory medicine · 2023Review
- Potential role for extracorporeal membrane oxygenation cardiopulmonary resuscitation (E-CPR) during in-hospital cardiac arrest in Australia: A nested cohort study.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2023Article
- Extracorporeal cardiopulmonary resuscitation dissemination and integration with organ preservation in the USA: ethical and logistical considerations.Critical care (London, England) · 2023Review
- ECPR may be the most effective intervention for refractory cardiac arrest-ever.Resuscitation · 2022Article
- A qualitative analysis of physician decision making in the use of extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest.Resuscitation plus · 2022Article
- Similarities in extracorporeal membrane oxygenation management across intensive care unit types in the United States: An analysis of the Extracorporeal Life Support Organization Registry.Artificial organs · 2022Article
- The association of modifiable mechanical ventilation settings, blood gas changes and survival on extracorporeal membrane oxygenation for cardiac arrest.Resuscitation · 2022Observational
- Resuscitation Using ECPR During In-Hospital Cardiac Arrest (RESCUE-IHCA) Mortality Prediction Score and External Validation.JACC. Cardiovascular interventions · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
BACKGROUND Outcomes from extracorporeal cardiopulmonary resuscitation (ECPR) are felt to be influenced by selective use, but the characteristics of those receiving ECPR are undefined. We demonstrate the relationship between individual patient and hospital characteristics and the probability of ECPR use. METHODS AND RESULTS We performed an observational analysis of adult inpatient cardiac arrests in the United States from 2000 to 2018 reported to the American Heart Association's Get With The Guidelines-Resuscitation registry restricted to hospitals that provided ECPR. We calculated case mix adjusted relative risk (RR) of receiving ECPR for individual characteristics. From 2000 to 2018, 129 736 patients had a cardiac arrest (128 654 conventional cardiopulmonary resuscitation and 1082 ECPR) in 224 hospitals that offered ECPR. ECPR use was associated with younger age (RR, 1.5 for <40 vs. 40-59 years; 95% CI, 1.2-1.8), no pre-existing comorbidities (RR, 1.4; 95% CI, 1.1-1.8) or cardiac-specific comorbidities (congestive heart failure [RR, 1.3; 95% CI, 1.2-1.5], prior myocardial infarction [RR, 1.4; 95% CI, 1.2-1.6], or current myocardial infarction [RR, 1.5; 95% CI, 1.3-1.8]), and in locations of procedural areas at the times of cardiac arrest (RR, 12.0; 95% CI, 9.5-15.1). ECPR decreased after hours (3-11 pm [RR, 0.8; 95% CI, 0.7-1.0] and 11 pm-7 am [RR, 0.6; 95% CI, 0.5-0.7]) and on weekends (RR, 0.7; 95% CI, 0.6-0.9). CONCLUSIONS Less than 1% of in-hospital cardiac arrest patients are treated with ECPR. ECPR use is influenced by patient age, comorbidities, and hospital system factors. Randomized controlled trials are needed to better define the patients in whom ECPR may provide a benefit.
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