Evidence map›Paper›PMID 32347146›Full record

Observational studyJournal of the American Heart Association2020

Procedural Volume and Outcomes After Percutaneous Coronary Intervention for Unprotected Left Main Coronary Artery Disease

Tadao Aikawa, Kyohei Yamaji, Toshiyuki Nagai, Shun Kohsaka, Kiwamu Kamiya, Kazunori Omote, Taku Inohara, Yohei Numasawa, Kenichi Tsujita, Tetsuya Amano and 2 more

Abstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Hospital-Level Variations in Outcomes and Readmissions Among Patients With STEMI and Cardiogenic Shock Receiving Mechanical Circulatory Support: Insights From a National Cohort.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
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  5. Application and Outcomes of Coronary Atherectomy in Acute Coronary Syndrome: A Report From the J-PCI Registry.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  6. Retrospective Analysis of the Thai Percutaneous Coronary Intervention Registry: Impacts of Center Volume and Operator Experience on Outcomes.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
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  13. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Tadao AikawaCardiovascular Research Center Icahn School of Medicine at Mount Sinai New York NY.
Kyohei YamajiJapanese Association of Cardiovascular Intervention and Therapeutics Tokyo Japan.
Toshiyuki NagaiDepartment of Cardiovascular Medicine Faculty of Medicine and Graduate School of Medicine Hokkaido University Sapporo Japan.
Shun KohsakaJapanese Association of Cardiovascular Intervention and Therapeutics Tokyo Japan.
Kiwamu KamiyaDepartment of Cardiovascular Medicine Faculty of Medicine and Graduate School of Medicine Hokkaido University Sapporo Japan.
Kazunori OmoteDepartment of Cardiovascular Medicine Faculty of Medicine and Graduate School of Medicine Hokkaido University Sapporo Japan.
Taku InoharaJapanese Association of Cardiovascular Intervention and Therapeutics Tokyo Japan.
Yohei NumasawaJapanese Association of Cardiovascular Intervention and Therapeutics Tokyo Japan.
Kenichi TsujitaJapanese Association of Cardiovascular Intervention and Therapeutics Tokyo Japan.
Tetsuya AmanoJapanese Association of Cardiovascular Intervention and Therapeutics Tokyo Japan.
Yuji IkariJapanese Association of Cardiovascular Intervention and Therapeutics Tokyo Japan.
Toshihisa AnzaiDepartment of Cardiovascular Medicine Faculty of Medicine and Graduate School of Medicine Hokkaido University Sapporo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background There is a limited evidence base to support the volume-outcome relationship in patients undergoing percutaneous coronary intervention (PCI) for unprotected left main coronary artery disease (UPLMD). This study aimed to evaluate the relationship between institutional and operator volume and in-hospital outcomes in patients undergoing PCI for unprotected left main coronary artery disease. Methods and Results We analyzed characteristics and clinical outcomes of 24 320 patients undergoing PCI for unprotected left main coronary artery disease at 1102 hospitals by 7244 operators using data from the Japanese nationwide J-PCI Registry (National PCI Data Registry) between January 2014 and December 2017. We classified institutions and operators into quartiles based on the mean annual volume of PCI. A generalized linear mixed-effects model was used to evaluate the association between institutional and operator PCI volume and in-hospital outcomes. Among the 24 320 patients, 4027 (16.6%), 6147 (25.3%), and 14 146 (58.2%) presented with ST-segment-elevation myocardial infarction, non-ST-segment-elevation acute coronary syndrome, and stable ischemic heart disease; their crude in-hospital mortality was 15%, 3.1%, and 0.3%, respectively. Compared with patients in the lowest quartile of institutional volume (1-216 PCIs/y), the adjusted odds ratio of in-hospital death in patients in the second (217-323 PCIs/y), third (324-487 PCIs/y), and fourth (488-3015 PCIs/y) quartile of institutional volume was 0.75 (95% CI, 0.51-1.10;

Indexed as

WorkloadAdolescentAdultAgedAged, 80 and overClinical CompetenceCoronary Artery DiseaseFemaleHospital MortalityHospitals, High-VolumeHospitals, Low-VolumeHumansJapanMaleMiddle AgedOutcome and Process Assessment, Health Caremortality/survivalpercutaneous coronary interventionrevascularizationunprotected left main coronary artery diseasevolume‐outcome relationship

Identifiers

PMID32347146
PMCPMC7428587

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.