ArticleBreast cancer research and treatment2020
Breast sensibility in bilateral autologous breast reconstruction with unilateral sensory nerve coaptation.
Article in Breast cancer research and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06930378 (Sensory Restoration in DIEP Free Flaps for Post-Mastectomy Breast Reconstruction After Breast Cancer), which is not on this map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Sensory Restoration in DIEP Free Flaps for Post-Mastectomy Breast Reconstruction After Breast Cancer: Comparing Non-sensitized Standard Technique to Direct Nerve Suture and to Autograft: A Three-arm, Randomized, Double-blinded Superiority Trial
Who cites it
13 citing papers in PubMed.
- Eight Women With Autologous Fat Transfer and Deep Inferior Epigastric Perforator Flap Breast Reconstruction: Which Do They Prefer, and Why?Plastic and reconstructive surgery. Global open · 2026Article
- Sensory Outcomes and Neurotization Techniques Following Mastectomies: A Comprehensive Systematic Review.Cancers · 2026Review
- Recipient vessel selection in autologous breast reconstruction: a narrative review of strategies and clinical implications.Gland surgery · 2026Review
- [Functional perforator flap: concept and clinical applications].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Review
- Optimal Recipient Nerve Selection for Breast Neurotization with Abdominal Flaps: A Comprehensive Meta-Analysis of Anterior and Lateral Intercostal Approaches.Journal of clinical medicine · 2025Review
- Meta-analysis of Objective Sensory Outcomes From 764 Breasts Shows Superior Sensation of Autologous Reconstruction With Neurotization.Plastic and reconstructive surgery. Global open · 2025Article
- Striving for higher levels of evidence in sensory restoration in DIEP flap breast reconstruction.Gland surgery · 2025Article
- Innervated breast reconstruction: a narrative review of neurotization techniques and outcomes.Annals of translational medicine · 2024Review
- The influence of a previous implant-based breast reconstruction on postoperative sensation of the deep inferior epigastric artery perforator flap.Breast cancer (Tokyo, Japan) · 2024Article
- Sensory recovery and the role of innervated flaps in autologous breast reconstruction-a narrative review.Gland surgery · 2023Review
- How to accurately preoperative screen nipple-sparing mastectomy candidate-a nomogram for predicting nipple-areola complex involvement risk in breast cancer patients.World journal of surgical oncology · 2023Article
- Functional and Psychosocial Outcomes following Innervated Breast Reconstruction: A Systematic Review.Plastic and reconstructive surgery. Global open · 2022Article
- The altering in sensory sensitivity: a current issue of female breast surgery.International journal of medical sciences · 2022Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatient satisfaction after breast reconstruction is dependent on both esthetics and functional outcomes. In an attempt to improve breast sensibility, a sensory nerve coaptation can be performed. The aim of this study was to objectify the sensory recovery in patients who, by chance, underwent bilateral autologous breast reconstruction with one innervated and one non-innervated flap. It must be emphasized that the intention was to coaptate the sensory nerves on both sides.
methodsThe cohort study was carried out in the Maastricht University Medical Center between August 2016 and August 2018. Patients were eligible if they underwent bilateral non-complex, autologous breast reconstruction with unilateral sensory nerve coaptation and underwent sensory measurements using Semmes-Weinstein monofilaments at 12 months of follow-up. Sensory outcomes were compared using t tests.
resultsA total of 15 patients were included, all contributing one innervated and one non-innervated flap. All patients had a follow-up of at least 12 months, but were measured at different follow-up points with a mean follow-up of 19 months. Sensory nerve coaptation was significantly associated with better sensation in the innervated breasts and showed better sensory recovery over time, compared to non-innervated breasts. Moreover, the protective sensation of the skin can be restored by sensory nerve coaptation.
conclusionsThe study demonstrated that sensory nerve coaptation leads to better sensation in the autologous reconstructed breast in patients who underwent bilateral breast reconstruction and, by chance, received unilateral sensory nerve coaptation.
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