Evidence map›Paper›PMID 32346754›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2020

Comparative analysis of rhinologic outcomes in Cushing disease and non-functioning pituitary adenoma in patients submitted to endoscopic endonasal transsphenoidal surgery.

Mariana D C Toro, Thiago L I Serrano, Fernando A L Marson, Carlos T Chone, Mateus Dal Fabbro, Eulália Sakano, Marcelo H Sampaio

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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mariana D C ToroDepartment of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medical Sciences, State University of Campinas, Tessália Viera de Camargo, 126, Campinas, São Paulo, 13083-887, Brazil. mdctoro@gmail.com.
Thiago L I SerranoDepartment of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medical Sciences, State University of Campinas, Tessália Viera de Camargo, 126, Campinas, São Paulo, 13083-887, Brazil.
Fernando A L MarsonPulmonary Physiology Lab, Department of Pediatrics, Faculty of Medical Sciences, Pediatrics Investigation Center, State University of Campinas, Campinas, São Paulo, Brazil.
Carlos T ChoneDepartment of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medical Sciences, State University of Campinas, Tessália Viera de Camargo, 126, Campinas, São Paulo, 13083-887, Brazil.
Mateus Dal FabbroDepartment of Neurosurgery, Faculty of Medical Sciences, State University of Campinas, Campinas, São Paulo, Brazil.
Eulália SakanoDepartment of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medical Sciences, State University of Campinas, Tessália Viera de Camargo, 126, Campinas, São Paulo, 13083-887, Brazil.
Marcelo H SampaioDepartment of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medical Sciences, State University of Campinas, Tessália Viera de Camargo, 126, Campinas, São Paulo, 13083-887, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAdrenocorticotropic hormone (ACTH) secreted by pituitary tumors lead to changes in nasal cavity anatomy and physiology. As a consequence of hormonal alteration, there is an abnormal soft tissue and an increased capillary fragility, inducting to a thinner mucosa that acts in the healing process. We compared post-operative nasal alterations in patients with Cushing's disease versus patients with non-functioning macroadenomas who underwent endoscopic endonasal transsphenoidal surgery.

methodsA retrospective study with 14 patients with Cushing's disease who underwent initial transsphenoidal endonasal surgery for an ACTH-secreting adenoma was conducted. Forty-two patients who underwent the same surgery for non-functioning adenomas were selected as controls. The following data were collected: operative technique, endoscopic alterations in late post-operative period and post-operative nasal complaints.

resultsThere were 13/14 (92.9%) females with Cushing disease versus 23/42 (54.8%) in the non-functioning adenoma group. Surgical approach was similar in both groups, with no differences in flap usage, turbinectomies or ethmoidectomies. No difference occurred concerning endoscopic alterations or nasal complaints in post-operative period.

conclusionsPost-operative results are similar, and healing could be expected to be equal.

Indexed as

AdenomaPituitary ACTH HypersecretionPituitary NeoplasmsEndoscopyFemaleHumansRetrospective StudiesTreatment OutcomeCushing syndromeNasal cavityNasal mucosaPituitary ACTH hypersecretionPituitary diseases

Identifiers

PMID32346754
OpenAlexW3018230158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.