ArticleThe journal of nutrition, health & aging2020
Prevalence and Its Associated Factors of Physical Frailty and Cognitive Impairment: Findings from the West China Health and Aging Trend Study (WCHAT).
Article in The journal of nutrition, health & aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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The trial behind it
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Association of malnutrition with cognitive frailty in China: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Prevalence of cognitive frailty among older adults in China: a systematic review and meta-analysis.BMJ open · 2023Pooled it
- Psychological and Social Factors Associated with Coexisting Frailty and Cognitive Impairment: A Systematic Review.Research on agingPooled it
- Association of the HALP score with baseline and incident physical-cognitive comorbidity and mortality: evidence from the WCHAT and UK Biobank cohorts.Frontiers in public health · 2026Article
- Article
- Closing the gap in dementia research by community-based cohort studies in the Chinese population.The Lancet regional health. Western Pacific · 2025Review
- The association between cognitive impairment and oral health or oral hygiene behaviors among multiethnic older adults in Western China: a cross-sectional multicenter study.BMC public health · 2025Article
- Associations Between Hearing Impairment and Dysphagia with Cognitive Frailty in Nursing Homes Older Adults.Clinical interventions in aging · 2025Article
- The geriatric nutrition risk index is longitudinally associated with incident Sarcopenia: evidence from a 5-year prospective cohort.Aging clinical and experimental research · 2024Article
- Association between chronic pain and cognitive frailty among middle-aged and elderly individuals: evidence from the China Health and Retirement Longitudinal Study.Frontiers in aging neuroscience · 2024Article
- Longitudinal associations between social support and sarcopenia: findings from a 5-year cohort study in Chinese aged ≥50 years.The journal of nutrition, health & aging · 2024Article
- Dynamics, association, and temporal sequence of cognitive function and frailty: a longitudinal study among Chinese community-dwelling older adults.BMC geriatrics · 2023Article
- Transitional Dynamics of Sarcopenia and Associations of Nutritional Indices with State Transitions in Chinese aged ≥ 50.The journal of nutrition, health & aging · 2023Article
- Potential association between frailty and pTau in community-dwelling older adults.BMC geriatrics · 2022Article
- Health Care Utilization and Out-of-Pocket Payments among Elderly with Cognitive Frailty in Malaysia.International journal of environmental research and public health · 2022Article
- Sarcopenia and the Brain.Arquivos de neuro-psiquiatria · 2021Article
- The Evolutionary Stage of Cognitive Frailty and Its Changing Characteristics in Old Adults.The journal of nutrition, health & aging · 2021Article
- Frailty in China: From Research to Practice.The journal of nutrition, health & aging · 2021Review
- Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss.GeroScience · 2020Review
- Editorial: Physical Frailty: A Biological Marker of Aging?The journal of nutrition, health & aging · 2020Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPrevious literature has reported that physical frailty (PF) closely associated with cognitive impairment (CI). In this study, we aim to describe and evaluate the prevalence and associated factors with different patterns of PF and cognitive impairment.
designA cross-sectional study. SETTING AND
participantsCommunity-dwelling older adults aged ≥60 from the West China Health and Aging Trend (WCHAT) study were included in this study. MEASUREMENTS: Participants were assessed the PF and cognitive impairment. PF was assessed using the physical phenotype as defined by Fried's criteria. Cognitive impairment was identified using the Short Portable Mental Status Questionnaire (SPMSQ). According different patterns of PF and cognitive impairment, participants were divided into 4 groups: not-PF and cognitive intact ( "neither" group), not-PF and cognitive impairment ("CI only" group), PF and cognitive intact ("PF only" group), and PF and cognitive impairment ("both" group). Multinomial logistic regression was used to explore the association between medical conditions and different patterns of PF and cognitive impairment after adjusting the demographic characteristics.
resultsAmong 4,103 participants (age 67.8 + 5.9 years, female 58.3%), 78.8%, 3.9%, 14.5% and 2.9% were "neither", "PF only", "CI only", and "both", respectively. The prevalence of "PF only", "CI only" and "both" were associated with age, lower education level and single status. In addition, there was substantial ethnicity heterogeneity in the prevalence of different patterns of PF and cognitive impairment. Comparing with "neither", PF and/or cognitive impairment had higher association with depression, ADLs impairment, and malnutrition. Of note, obesity was only significantly associated with "PF only", but not associated with "CI only" or "both".
conclusionsWe found the substantial demographic and medical conditions disparities in different patterns of PF and cognitive impairment. Further research should focus on the efficient and practical screen to predict the risk of "PF only", "CI only" and "both".
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