ArticleThe journal of nutrition, health & aging2020
Cognitive Frailty as a Risk Factor for Incident Disability During Late Life: A 24-Month Follow-Up Longitudinal Study.
Article in The journal of nutrition, health & aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Impact of frailty, mild cognitive impairment and cognitive frailty on adverse health outcomes among community-dwelling older adults: A systematic review and meta-analysis.Frontiers in medicine · 2022Pooled it
- Association between Cognitive Frailty and Adverse Outcomes among Older Adults: A Meta-Analysis.The journal of nutrition, health & aging · 2022Pooled it
- Cognitive frailty as a predictor of adverse outcomes among older adults: A systematic review and meta-analysis.Brain and behavior · 2021Pooled it
- Increased Risk of Transition to Institutional Care Among Community-Dwelling Older Adults With Cognitive Frailty: A Competing Risks Survival Analysis.International journal of geriatric psychiatry · 2026Article
- Sleep quality in older adults with cognitive frailty: current status and influencing factors.BMC geriatrics · 2025Article
- Comparisons of four cognitive-frailty measures in predicting dementia and disability.BMC geriatrics · 2025Article
- Impact of Modifiable Factors Associated with Physical Frailty and Cognitive Impairment Trajectory of Older Adults: Using the Korean Longitudinal Study of Aging 2006-2018.Healthcare (Basel, Switzerland) · 2025Article
- The impact of exercise interventions on cognitive frailty: a scoping review of outcomes and biological mechanisms.Frontiers in public health · 2025Article
- Construction and validation of a cognitive frailty risk prediction model for elderly patients with colorectal cancer.Frontiers in aging neuroscience · 2025Article
- Synergistic effects of cognitive frailty and comorbidities on disability: a community-based longitudinal study.BMC geriatrics · 2024Article
- Consensus Paper: Cerebellum and Ageing.Cerebellum (London, England) · 2024Review
- Utilization of Japanese long-term care-related data including Kaigo-DB: An analysis of current trends and future directions.Global health & medicine · 2024Review
- Overlapping status of frailty and fear of falling: an elevated risk of incident disability in community-dwelling older adults.Aging clinical and experimental research · 2023Article
- Differential effects of lifestyle activities on disability incidence based on neighborhood amenities.BMC geriatrics · 2023Observational
- Cognitive Frailty and Functional Disability Among Community-Dwelling Older Adults: A Systematic Review.Innovation in aging · 2023Review
- Health Care Utilization and Out-of-Pocket Payments among Elderly with Cognitive Frailty in Malaysia.International journal of environmental research and public health · 2022Article
- Cerebral small vessel disease is associated with concurrent physical and cognitive impairments at preclinical stage.Cerebral circulation - cognition and behavior · 2022Article
- Long sleep duration is associated with cognitive frailty among older community-dwelling adults: results from West China Health and Aging Trend study.BMC geriatrics · 2021Article
- Cognitive frailty is a robust predictor of falls, injuries, and disability among community-dwelling older adults.BMC geriatrics · 2021Article
- Life Satisfaction and the Relationship between Mild Cognitive Impairment and Disability Incidence: An Observational Prospective Cohort Study.International journal of environmental research and public health · 2021Observational
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAssociation between cognitive frailty as identified by a new operational definition and incident disability in the community setting remains unclear. This will be the catalyst for preventive interventions designed to treat adverse health problems among elderlies.
designA 24-month follow-up longitudinal study on a community-based cohort.
settingCommunity-setting.
participantsParticipants included a total of 9,936 older adults aged 65 years or older. MEASUREMENTS: Frailty was characterized as slow walking speed or/and muscle weakness represented by grip strength. Cognitive function was assessed according to several tests. Cognitive impairment was defined below the age-education reference threshold. Participants were categorized into the four groups: robust, cognitive impairment alone, frailty alone, and cognitive frailty (both frail and cognitive impairment). Incident disability data was extracted from the Japanese Long-Term Care system.
resultsThe prevalence of cognitive frailty was 11.2%. The cumulative incidence rates of incident disability in each group were also estimated (robust, 9.6/1,000 person-years (95% CI 7.9 to 11.7); cognitive impairment, 21.3/1,000 person years (95% CI 16.3 to 27.7); frailty, 45.4/1,000 person years (95% CI 39.5 to 52.3); and cognitive frailty, 79.9/1,000 person years (95% CI 68.6 to 93.1)). Adjusted Cox proportional hazard model revealed that the cognitive frailty group had the highest hazard ratio (HR 3.86, 95%CI 2.95 - 5.05, P < 0.001).
conclusionsA proper operational definition was developed to determine cognitive frailty among elderlies. Cognitive frailty is more associated with incident disability in community-setting than cognitive impairment or physical frailty alone.
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