Evidence map›Paper›PMID 32346667›Full record

ArticleAdvances in neurotoxicology2018

Neurodevelopmental Effects of Mercury.

Cláudia S Oliveira, Pablo A Nogara, Daniel M P Ardisson-Araújo, Michael Aschner, João B T Rocha, José G Dórea

Abstract read
In one paragraph

Article in Advances in neurotoxicology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Prenatal Mercury Exposure and Neurodevelopment up to the Age of 5 Years: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  2. Mercury and Prenatal Growth: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  3. Article
  4. Article
  5. Review
  6. Mercury-induced excitotoxicity in autism spectrum disorder: disruption of glutamatergic homeostasis and the therapeutic role of the selenium-glutathione axis.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Comparative Physiological Responses ofPlants (Basel, Switzerland) · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Diphenyl Diselenide and SARS-CoV-2:Journal of chemical information and modeling · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cláudia S OliveiraPrograma de Pós-graduação em Ciências Biológicas: Bioquímica Toxicológica, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
Pablo A NogaraPrograma de Pós-graduação em Ciências Biológicas: Bioquímica Toxicológica, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
Daniel M P Ardisson-AraújoPrograma de Pós-graduação em Ciências Biológicas: Bioquímica Toxicológica, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
Michael AschnerDepartment of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York, NY, USA.
João B T RochaDepartamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
José G DóreaProfessor Emeritus, Faculdade de Ciências da Saúde, Universidade de Brasília, Brasília, DF, Brazil.

Funding

Mechanisms of Manganese NeurotoxicityR01ES010563 · NIEHS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Michael Aschner, Aaron B Bowman · 2001 to 2026
$11.9M
Mechanisms of Methylmercury Induced Neuron ToxicityR01ES007331 · NIEHS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Michael Aschner, Aaron B Bowman · 1996 to 2026
$10.6M
Genetic Modulation of MeHg-Induced Oxidative Stress in the Developing BrainR01ES020852 · NIEHS · VANDERBILT UNIVERSITY · PI ASCHNER, MICHAEL · 2012 to 2016
$1.8M
NIEHS NIH HHS R01 ES007331NIEHS NIH HHS R01 ES010563NIEHS NIH HHS R01 ES020852
6 · The paper itself

Abstract

The toxicology of mercury (Hg) is of concern since this metal is ubiquitously distributed in the environment, and living organisms are routinely exposed to Hg at low to high levels. The toxic effects of Hg are well studied and it is known that they may differ depending on the Hg chemical species. In this chapter, we emphasize the neurotoxic effects of Hg during brain development. The immature brain is more susceptible to Hg exposure, since all the Hg chemical forms, not only the organic ones, can harm it. The possible consequences of Hg exposure during the early stages of development, the additive effects with other co-occurring neurotoxicants, and the known mechanisms of action and targets will be addressed in this chapter.

Indexed as

brainHMM-SHLMM-SHMercurythimerosal

Identifiers

PMID32346667
PMCPMC7188190

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.