Evidence map›Paper›PMID 32346602›Full record

ArticleInternational journal of cardiology. Heart & vasculature2020

Ventilatory power, a cardiopulmonary exercise testing parameter for the prediction of pulmonary hypertension at right heart catheterization.

Michele Correale, Ilenia Monaco, Armando Ferraretti, Lucia Tricarico, Monica Sicuranza, Anna Maria Gallotta, Ennio Sascia Formica, Gianfranco Acanfora, Matteo Di Biase, Natale Daniele Brunetti

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In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Michele CorrealeCardiology Department, Ospedali Riuniti University Hospital, Foggia, Italy.
Ilenia MonacoDepartment of Medical & Surgical Sciences, University of Foggia, Foggia, Italy.
Armando FerrarettiDepartment of Medical & Surgical Sciences, University of Foggia, Foggia, Italy.
Lucia TricaricoDepartment of Medical & Surgical Sciences, University of Foggia, Foggia, Italy.
Monica SicuranzaDepartment of Medical & Surgical Sciences, University of Foggia, Foggia, Italy.
Anna Maria GallottaDepartment of Medical & Surgical Sciences, University of Foggia, Foggia, Italy.
Ennio Sascia FormicaDepartment of Medical & Surgical Sciences, University of Foggia, Foggia, Italy.
Gianfranco AcanforaCardiology Department, Ospedali Riuniti University Hospital, Foggia, Italy.
Matteo Di BiaseCardiology Department, Ospedali Riuniti University Hospital, Foggia, Italy.
Natale Daniele BrunettiDepartment of Medical & Surgical Sciences, University of Foggia, Foggia, Italy.
University of Foggia · ITOspedali Riuniti di Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral cardiopulmonary exercise test (CPET) parameters (peak VO

aimTo ascertain possible correlations between VP derived at CPET and hemodynamic parameters at right heart catheterization (RHC) indicative of PH.

methodsForty-seven consecutive outpatients with suspect of PAH were assessed by CPET and RHC; VP was defined as peak SBP divided by the minute ventilation-CO2 production slope at CPET and Diastolic Pressure Gradient (DPG), Trans-pulmonary Pressure Gradient (TPG), mean pulmonary artery pressure (mPAP) and pulmonary vascular resistance (PVR) at RHC were also assessed and compared with VP.

resultsVP values were inversely related to mPAP (r -0.427, p 0.003), DPG (r -0.36, p 0.019), TPG (r: -0.43, p 0.004), and PVR (r -0.52, p 0.001). Correlations remained significant even after correction at multivariate analysis for age and gender. VP values below median identified subjects with mPAP ≥ 25 mmHg with an odds ratio of 4.5 (95% confidence interval 1.05-19.36, p < 0.05), an accuracy of 0.712 at ROC curve analysis (95% confidence interval 0.534-0.852, p < 0.05) and a positive predictive power 82%.

conclusionsIn patients with suspected PAH, VP assessed at CPET might provide further information in predicting PAH at RHC. Correlations with PVR and DPG may be helpful in differentiating patients with isolated post-capillary PH from those with combined post-capillary and pre-capillary.

Indexed as

6MWT, 6-minute walking testBMI, body mass indexCardiopulmonary exercise testCI, cardiac indexCOPD, chronic obstructive pulmonary diseaseCpc-PH, combined post-capillary and pre-capillary pulmonary hypertensionCPET, cardiopulmonary exercise testingDiastolic pressure gradientDPG, diastolic pressure gradient (diastolic PAP – mean PAWP)ECG, electrocardiogramEF, ejection fractionIpc-PH, isolated post-capillary pulmonary hypertensionmPAP, mean pulmonary arterial pressureNYHA, New York Heart AssociationPAH, pulmonary arterial hypertensionPAsP, systolic pulmonary arterial pressurePAWP, pulmonary artery wedge pressurePeak VO2, peak oxygen consumptionPetCO2, end-tidal carbon dioxide tensionPH, pulmonary hypertensionPulmonary vascular resistancePVR, pulmonary vascular resistanceRAP, right atrial pressureRHC, right heart catheterizationRV, right ventricleTPG, transpulmonary pressure gradient (mean PAP – mean PAWP)Transpulmonary pressure gradientVentilatory powerVE/VCO2, minute ventilation- carbondioxide production ratioVE, ventilationVP, ventilatory power

Identifiers

PMID32346602
PMCPMC7178492
OpenAlexW3018613467

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.