ArticleAlzheimer's & dementia (New York, N. Y.)2020
DNA methylation in APOE: The relationship with Alzheimer's and with cardiovascular health.
Article in Alzheimer's & dementia (New York, N. Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Deconfounded-Debiased Estimation and Inference for High-Dimensional Mediation Analysis With Pervasive Hidden Confounders.Statistics in medicine · 2026Article
- Article
- Haplotype-resolved DNA methylation at theNPJ dementia · 2026Article
- Is the Relationship Between Cardiovascular Disease and Alzheimer's Disease Genetic? A Scoping Review.Genes · 2024Article
- Plasma Proteomic Biomarkers in Alzheimer's Disease and Cardiovascular Disease: A Longitudinal Study.International journal of molecular sciences · 2024Article
- APOE 5'UTR Methylation Pattern Analysis in Blood and Brain Tissue from Alzheimer's Disease Affected Patients.Aging and disease · 2024Article
- Epigenetics in Alzheimer's Disease: A Critical Overview.International journal of molecular sciences · 2024Review
- The Impact of Apolipoprotein E (Biology · 2023Review
- A Review of the Recent Advances in Alzheimer's Disease Research and the Utilization of Network Biology Approaches for Prioritizing Diagnostics and Therapeutics.Diagnostics (Basel, Switzerland) · 2022Review
- APOE gene region methylation is associated with cognitive performance in middle-aged urban adults.Neurobiology of aging · 2022Article
- Association of DNA methylation and genetic variations of theBiomedical reports · 2022Article
- Associations of ARHGAP26 Polymorphisms with Alzheimer's Disease and Cardiovascular Disease.Journal of molecular neuroscience : MN · 2022Article
- Article
- Apolipoprotein E and Atherosclerosis.Current atherosclerosis reports · 2021Review
- Epigenetics of Alzheimer's Disease.Biomolecules · 2021Review
- Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles.Genome medicine · 2021Article
- The Effect and Mechanism of Cholesterol and Vitamin BFrontiers in aging neuroscience · 2021Article
- DNA methylation in APOE: The relationship with Alzheimer's and with cardiovascular health.Alzheimer's & dementia (New York, N. Y.) · 2020Article
- Alzheimer's disease genetic risk: Top African American risk allele frequencies and genetic architecture among Mexican-, African-, and non-Hispanic White Americans.Alzheimer's & dementia (New York, N. Y.)Article
- Top Alzheimer's disease risk allele frequencies differ in HABS-HD Mexican- versus Non-Hispanic White Americans.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
introductionGenetic variation in the apolipoprotein E (
methodsWe assessed blood-based DNA methylation at 13 CpGs in the
resultsDNA methylation at two CpGs was associated with the ratio of total cholesterol and HDL cholesterol, but not with cognition, family history of AD, or the risk of CVD. DISCUSSION:
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.