Evidence map›Paper›PMID 32346536›Full record

ArticleFrontiers in cell and developmental biology2020

ESCRT Machinery Mediates Cytokinetic Abscission in the Unicellular Red Alga

Fumi Yagisawa, Takayuki Fujiwara, Tokiaki Takemura, Yuki Kobayashi, Nobuko Sumiya, Shin-Ya Miyagishima, Soichi Nakamura, Yuuta Imoto, Osami Misumi, Kan Tanaka and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Diversity, Origin and Evolution of the ESCRT Systems.bioRxiv : the preprint server for biology · 2024
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 2 countries.

Fumi YagisawaCenter for Research Advancement and Collaboration, University of the Ryukyus, Okinawa, Japan.
Takayuki FujiwaraDepartment of Gene Function and Phenomics, National Institute of Genetics, Shizuoka, Japan.
Tokiaki TakemuraLaboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.
Yuki KobayashiLaboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.
Nobuko SumiyaDepartment of Gene Function and Phenomics, National Institute of Genetics, Shizuoka, Japan.
Shin-Ya MiyagishimaDepartment of Gene Function and Phenomics, National Institute of Genetics, Shizuoka, Japan.
Soichi NakamuraLaboratory of Cell and Functional Biology, Faculty of Science, University of the Ryukyus, Okinawa, Japan.
Yuuta ImotoDepartment of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Osami MisumiDepartment of Biological Science and Chemistry, Faculty of Science, Yamaguchi University, Yamaguchi, Japan.
Kan TanakaLaboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.
Haruko KuroiwaDepartment of Chemical and Biological Science, Japan Women's University, Tokyo, Japan.
Tsuneyoshi KuroiwaDepartment of Chemical and Biological Science, Japan Women's University, Tokyo, Japan.
Japan Women's University · JPLife Science Institute · JPUniversity of the Ryukyus · JPJapan Science and Technology Agency · JPJohns Hopkins Medicine · USNational Institute of Genetics · JPThe Graduate University for Advanced Studies, SOKENDAI · JPTokyo Institute of Technology · JPYamaguchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In many eukaryotes, cytokinesis proceeds in two successive steps: first, ingression of the cleavage furrow and second, abscission of the intercellular bridge. In animal cells, the actomyosin contractile ring is involved in the first step, while the endosomal sorting complex required for transport (ESCRT), which participates in various membrane fusion/fission events, mediates the second step. Intriguingly, in archaea, ESCRT is involved in cytokinesis, raising the hypothesis that the function of ESCRT in eukaryotic cytokinesis descended from the archaeal ancestor. In eukaryotes other than in animals, the roles of ESCRT in cytokinesis are poorly understood. To explore the primordial core mechanisms for eukaryotic cytokinesis, we investigated ESCRT functions in the unicellular red alga

Indexed as

Cyanidioschyzon merolaecytokinesiscytokinetic abscissionESCRTred alga

Identifiers

PMID32346536
PMCPMC7169423
OpenAlexW3014916295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.